基于运动表象的脑机接口训练对亚急性期脑卒中患者手功能康复的效果

doi:10.3969/j.issn.1006-9771.2023.01.010

Abstract

Abstract:

Objective To observe the effect of brain-computer interface (BCI) training based on motor imagery on hand function in hemiplegic patients with subacute stroke.

Methods From June, 2020 to December, 2021, 40 patients with hemiplegia in subacute stroke from Department of Rehabilitation Medicine, Fifth Affiliated Hospital of Zhengzhou University were divided into control group (n = 20) and experimental group (n = 20) using random number table. Both groups accepted medication and routine comprehensive rehabilitation, while the control group accepted hand rehabilitation robot training, and the experimental group accepted the robot training using motor imagery-based BCI, for four weeks. They were assessed with Fugl-Meyer Assessment-Upper Extremities (FMA-UE), modified Barthel Index, modified Ashworth scale, and measured integrated electromyogram of the superficial finger flexors, finger extensors and short thumb extensors of the affected forearm during maximum isometric voluntary contraction with surface electromyography.

Results Two patients in the control group and one in the experimental group dropped off. All the indexes improved in both groups after treatment (t > 2.322, Z > 2.631, P < 0.05), and they were better in the experimental group than in the control group (t > 2.227, Z > 2.078, P < 0.05), except the FMA-UE score of wrist.

Conclusion Motor imagery-based BCI training is more effective on hand function and activities of daily living in hemiplegic patients with subacute stroke.

Key words: stroke, motor imagery, brain-computer interface, hand function

CLC Number:

R743.3

LIU Mingyue, LI Zhe, CAO Yongsheng, HAO Daojian, SONG Xueyi. Effect of brain-computer interface training based on motor imagery on hand function for subacute stroke patients[J]. Chinese Journal of Rehabilitation Theory and Practice, 2023, 29(1): 71-76.

Figures/Tables 9

References 38

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组别	n	性别 (男/女)/n	年龄/岁	病程/d	偏瘫侧 (左/右)/n	卒中类型 (梗死/出血)/n	MMSE
对照组	18	10/8	52.89±13.07	90.28±52.15	7/11	8/10	26.17±1.25
试验组	19	15/4	51.26±11.06	98.26±48.25	10/9	5/14	26.53±1.65
χ²/t值		0.650	0.409	-0.484	0.703	1.333	-0.746
P值		0.420	0.685	0.632	0.402	0.248	0.461

组别	n	治疗前	治疗后	t值	P值
对照组	18	23.94±6.95	27.22±8.31	2.322	0.026
试验组	19	25.37±9.27	33.58±8.47	2.850	0.007
t值		0.529	2.304
P值		0.600	0.027

组别	n	治疗前	治疗后	Z值	P值
对照组	18	3.00(2.00, 4.00)	5.00(4.50, 6.25)	3.596	< 0.001
试验组	19	3.00(3.00, 4.00)	5.00(4.50, 6.25)	3.752	< 0.001
Z值		0.818	1.828
P值		0.443	0.075

组别	n	治疗前	治疗后	Z值	P值
对照组	18	4.00(3.00, 6.00)	7.00(5.50, 8.00)	3.666	< 0.001
试验组	19	4.00(3.00, 6.00)	8.00(7.00, 10.00)	3.860	< 0.001
Z值		0.492	2.139
P值		0.641	0.034

组别	n	治疗前	治疗后	t值	P值
对照组	18	32.50±12.16	45.56±16.08	6.200	< 0.001
试验组	19	34.73±9.05	58.16±12.27	10.346	< 0.001
t值		0.637	2.689
P值		0.528	0.011

Effect of brain-computer interface training based on motor imagery on hand function for subacute stroke patients

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组别	n	治疗前	治疗后	Z值	P值
对照组	18	2.00(1.50, 2.00)	1.50(1.50, 2.00)	2.631	0.009
试验组	19	1.50(1.00, 1.50)	1.00(1.00, 1.50)	3.852	< 0.001
Z值		1.201	2.078
P值		0.245	0.039

组别	n	治疗前	治疗后	Z值	P值
对照组	18	35.16(32.15, 41.23)	45.88(42.18, 59.40)	3.724	< 0.001
试验组	19	35.46(30.45, 43.26)	54.03(45.15, 63.42)	3.823	< 0.001
Z值		0.547	2.335
P值		0.599	0.020

组别	n	治疗前	治疗后	t值	P值
对照组	18	30.44±8.55	40.17±9.21	3.285	0.002
试验组	19	31.05±9.21	46.38±7.72	5.560	< 0.001
t值		0.208	2.227
P值		0.836	0.033

组别	n	治疗前	治疗后	t值	P值
对照组	18	31.17±9.41	40.39±9.88	11.987	< 0.001
试验组	19	32.74±7.04	47.74±6.22	12.259	< 0.001
t值		0.577	2.724
P值		0.568	0.010

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