老年人平衡功能的脑网络变化：基于功能性近红外线光谱研究

doi:10.3969/j.issn.1006-9771.2023.02.013

Abstract

Abstract:

Objective To study the brain network during balance control tasks in older adults. Methods From January to April, 2022, 22 healthy young adults and 20 healthy older adults were recruited from the Fifth Affiliated Hospital of Guangzhou Medical University and communities. They were asked to finish standing tasks on the plantar pressure plate with eyes opening and closing, while the functional connectivities (FC) of prefrontal cortex (PFC) and primary motor cortex (PMC) were measured with functional near-infrared spectroscopy. Results Compared with the young adults, the area of the ellipse (Z = -2.884, P < 0.01) and the maximum swing (Z = -2.481, P < 0.05) increased in the older adults as eyes closing. During the standing task, the intra-FC of left (t = 2.978, P < 0.01) and right (Z = -3.123, P < 0.01) PFC decreased in the older adults, and the inter-FC of right PMC to left PFC (t = 2.087, P < 0.05) and right PFC to left PFC (t = 3.471, P < 0.001) decreased, too. Conclusion The FC of PFC decreased in healthy older adults during balance control tasks, which may be a indicator for aging brain.

Key words: older adults, aging brain, balance control, functional near-infrared spectroscopy, functional connectivity, prefrontal cortex

CLC Number:

R743.3

LUO Qihang, WU Yuxi, ZHANG Jiaxuan, LI Wanying, OU Haining, LIN Qiang, LIANG Junjie. Brain network during balance in older adults: a functional near-infrared spectroscopy study[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(2): 238-242.

Figures/Tables 3

References 26

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平衡参数	状态	年轻人(n = 22)	老年人(n = 20)	t值/Z值	P值
球长度/mm	睁眼	203.037±40.888	211.073±64.185	-0.489	0.628
球长度/mm	闭眼	228.127±62.178	234.149±50.550	-0.342	0.732
椭圆面积/cm²	睁眼	22.968±21.178	31.475±20.742	-1.436^a	0.151
椭圆面积/cm²	闭眼	35.489±26.258	96.252±90.073	-2.884^a	0.004
平均速度/(mm·s^-1)	睁眼	10.219±2.044	10.634±3.230	-0.503	0.618
平均速度/(mm·s^-1)	闭眼	11.382±3.124	11.678±2.535	-0.334	0.740
平均X/mm	睁眼	1.247±8.435	1.968±9.546	-0.260	0.796
平均X/mm	闭眼	0.041±7.982	3.255±8.292	-0.504^a	0.614
平均Y/mm	睁眼	-21.258±10.856	-25.837±11.179	1.346	0.186
平均Y/mm	闭眼	-21.583±11.161	-27.516±10.339	1.782	0.082
椭圆倾斜角/°	睁眼	86.091±42.808	85.850±48.930	-0.101^a	0.920
椭圆倾斜角/°	闭眼	86.455±46.030	96.400±42.057	-0.667^a	0.504
椭圆偏心角/°	睁眼	0.514±0.244	0.398±0.276	-1.537^a	0.124
椭圆偏心角/°	闭眼	0.458±0.222	0.471±0.307	-0.156	0.879
最大摆动/mm	睁眼	1.461±0.413	1.574±0.578	-0.735	0.467
最大摆动/mm	闭眼	2.588±3.989	2.646±1.379	-2.481^a	0.013
最小摆动/mm	睁眼	0.013±0.010	0.013±0.010	-0.054^a	0.957
最小摆动/mm	闭眼	0.012±0.010	0.016±0.007	-1.467^a	0.142

ROI	年轻人 (n = 22)	老年人 (n = 20)	t值/Z值	P值
LPMC	0.706±0.222	0.691±0.199	-0.529^a	0.597
LPFC	0.747±0.118	0.562±0.264	2.978	0.005
RPMC	0.653±0.189	0.641±0.177	0.220	0.827
RPFC	0.737±0.118	0.545±0.205	-3.123^a	0.002
LPMC-RPMC	0.643±0.190	0.594±0.194	0.821	0.416
LPMC-RPFC	0.539±0.183	0.441±0.220	1.564	0.126
LPMC-LPFC	0.529±0.182	0.481±0.205	0.811	0.422
RPMC-RPFC	0.538±0.168	0.431±0.185	1.968	0.056
RPMC-LPFC	0.534±0.168	0.415±0.202	2.087	0.043
RPFC-LPFC	0.677±0.128	0.473±0.240	3.471	< 0.001

Brain network during balance in older adults: a functional near-infrared spectroscopy study

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