低频重复经颅磁刺激联合双侧对称运动训练对脑卒中患者上肢运动功能的效果

doi:10.3969/j.issn.1006-9771.2023.03.002

Abstract

Abstract:

Objective To explore low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with bilateral isokinematic training (BIT) on upper limb motor function and activities of daily living of stroke patients.

Methods From September, 2021 to September, 2022, 60 stroke inpatients in Zhejiang Provincial People's Hospital were randomly divided into rTMS group (n = 20), BIT group (n = 20) and combination group (n = 20). All the patients accepted routine rehabilitation, moreover, rTMS group accepted 1 Hz rTMS on healthy side, BIT group accepted BIT, and the combination group accepted the combination of 1 Hz rTMS on healthy side and BIT, for four weeks. They were evaluated with Fugl-Meyer Assessment-Upper Extremities (FMA-UE), Wolf Motor Function Test (WMFT), Carroll Upper Extremities Function Test (UEFT) and modified Barthel Index (MBI) before and after treatment.

Results The scores of FMA-UE, WMFT, UEFT and MBI significantly improved in all the groups after treatment (|t| > 5.052, P< 0.001), and improved the most in the combination group (F> 9.834, P< 0.001).

Conclusion Both low-frequency rTMS and BIT can effectively improve upper limb motor function and activities of daily living of stroke patients, and the combination of them is more effective.

Key words: stroke, repetitive transcranial magnetic stimulation, bilateral isokinematic training, upper limb, motor function

CLC Number:

R743.3

SUN Fengbao, ZENG Yaqin, OUYANG Yao, JIN Zhenhua, ZHANG Xiaofeng. Effect of low frequency repetitive transcranial magnetic stimulation combined with bilateral isokinematic training on upper limb motor function of stroke patients[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(3): 256-261.

Figures/Tables 5

References 37

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组别	n	性别(男/女)/n	年龄/岁	病程/d	卒中性质(梗死/出血)/n	偏瘫侧(左/右)/n
rTMS组	20	10/10	56.75±10.77	24.00±5.40	13/7	9/11
BIT组	20	14/6	56.05±11.90	24.60±4.36	12/8	12/8
联合组	20	14/6	57.70±10.48	23.85±4.57	13/7	8/12
χ²/F值		2.297	0.112	0.137	0.144	1.735
P值		0.317	0.894	0.872	0.931	0.420

组别	n	治疗前	治疗后	t值	P值
rTMS组	20	17.40±3.07	24.70±4.90	-6.942	< 0.001
BIT组	20	17.25±2.81	26.15±4.74	-8.529	< 0.001
联合组	20	16.90±2.75	31.95±3.14^a,b	-15.232	< 0.001
F值		0.159	15.685
P值		0.853	< 0.001

组别	n	治疗前	治疗后	t值	P值
rTMS组	20	30.95±4.77	37.45±5.57	-5.052	< 0.001
BIT组	20	31.15±4.25	38.70±4.61	-8.115	< 0.001
联合组	20	31.90±4.89	44.65±6.17^a,b	-9.447	< 0.001
F值		0.233	9.834
P值		0.793	< 0.001

组别	n	治疗前	治疗后	t值	P值
rTMS组	20	28.20±4.43	37.05±4.70	-18.988	< 0.001
BIT组	20	28.35±3.84	38.90±4.55	-35.828	< 0.001
联合组	20	28.30±3.40	45.65±4.02^a,b	42.764	< 0.001
F值		0.008	20.87
P值		0.992	< 0.001

组别	n	治疗前	治疗后	t值	P值
rTMS组	20	39.35±6.55	53.05±7.12	-14.271	< 0.001
BIT组	20	38.90±5.61	55.95±7.21	-12.590	< 0.001
联合组	20	38.75±6.58	62.70±6.14^a,b	-25.510	< 0.001
F值		0.05	10.483
P值		0.952	< 0.001

Effect of low frequency repetitive transcranial magnetic stimulation combined with bilateral isokinematic training on upper limb motor function of stroke patients

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