双侧序贯重复经颅磁刺激干预脑卒中患者上肢运动功能的效果

doi:10.3969/j.issn.1006-9771.2023.08.009

Abstract

Abstract:

Objective To observe the effect of bilateral sequential repetitive transcranial magnetic stimulation on the motor function of upper limbs in stroke patients.
Methods From December, 2020 to December, 2022, 62 stroke inpatients in the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine were included. They were randomly divided into control group (n = 31) and observation group (n = 31). Both groups accepted conventional medicine and rehabilitation, as well as electroacupuncture antagonistic muscle therapy. Before electroacupuncture, the observation group acceped low-frequency repetitive transcranial magnetic stimulation at primary motor cortex (M1) on the healthy side, followed by intermittent theta burst stimulation at M1 on the affected side, for four weeks. They were assessed with Fugl-Meyer Assessment-Upper Extremities (FMA-UE), modified Barthel Index (MBI) and modified Ashworth Scale (MAS), and motor evoked potential (MEP) latency was compared before and after treatment.
Results One patient dropped down in the observation group, and no adverse event happened. After treatment, the scores of FMA-UE and MBI significantly increased (|t| > 9.953, P < 0.001), and the score of MAS and the latency of MEP significantly decreased (|t| > 5.043, P < 0.001) in both groups; while all of them were better in the observation group than in the control group (|t| > 2.237, P < 0.05).
Conclusion Bilateral sequential repetitive transcranial magnetic stimulation can effectively promote the recovery of upper limb motor function in stroke patients.

Key words: stroke, repetitive transcranial magnetic stimulation, electroacupuncture, upper limbs, motor function

CLC Number:

R743.3

CHEN Yiting, WANG Qian, CUI Shenhong, LI Yingcai, ZHANG Siyu, WEI Yanxu, REN Hui, LENG Jun, CHEN Bin. Effect of bilateral sequential repetitive transcranial magnetic stimulation on motor function of upper limbs in stroke patients[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(8): 926-932.

Figures/Tables 5

References 33

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组别	n	性别/n		年龄/岁	病程/d	病灶性质/n		偏瘫侧/n
组别	n	男	女	年龄/岁	病程/d	脑梗死	脑出血	右	左
对照组	31	16	15	65.30±7.02	63.58±19.42	23	8	13	18
观察组	30	18	12	65.80±6.12	63.17±18.33	20	10	14	16
t/χ²值		0.435		0.183	0.086	0.415		0.138
P值		0.510		0.857	0.932	0.519		0.799

组别	n	治疗前	治疗后	t值	P值
对照组	31	26.450±3.686	35.320±4.614	-14.151	< 0.001
观察组	30	24.830±3.228	42.100±6.950	-16.220	< 0.001
t值		-1.822	4.499
P值		0.074	< 0.001

组别	n	治疗前	治疗后	t值	P值
对照组	31	43.548±4.515	51.032±3.341	-14.802	< 0.001
观察组	30	42.000±6.602	54.533±8.025	-9.953	< 0.001
t值		-1.022	2.237
P值		0.288	0.029

组别	n	治疗前	治疗后	t值	P值
对照组	31	1.903±1.165	1.387±0.955	5.043	< 0.001
观察组	30	1.833±0.950	0.800±0.610	8.464	< 0.001
t值		-0.256	-2.851
P值		0.799	0.006

组别	n	治疗前	治疗后	t值	P值
对照组	31	34.677±3.208	31.645±2.470	12.042	< 0.001
观察组	30	34.833±2.780	27.933±3.279	12.478	< 0.001
t值		1.502	-5.004
P值		0.139	< 0.001

Effect of bilateral sequential repetitive transcranial magnetic stimulation on motor function of upper limbs in stroke patients

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