多靶区经颅直流电刺激对健康成年人工作记忆-姿势控制双任务表现的影响

doi:10.3969/j.issn.1006-9771.2024.01.003

Abstract

Abstract:

Objective To investigate the effect of multi-target transcranial direct current stimulation (tDCS) and single-target tDCS on the performance of working memory-postural control dual-task in healthy adults, and to compare the regulatory effect of the two stimulation protocols.

Methods From November, 2020 to February, 2021, 19 healthy adults in Shanghai University of Sport were recruited and randomly accepted multi-target tDCS, single-target tDCS and sham stimulation with at least one week interval between any two stimulation protocols. The target areas of multi-target tDCS included left dorsal lateral prefrontal cortex (L-DLPFC) and bilateral primary motor cortex (M1), and single-tDCS only applied to L-DLPFC. Before and after stimulation, participants completed walking and standing balance tests under single task and dual-task conditions with the second task being a N-back task. The dual-task postural control performance, dual-task cost (DTC) and working memory performance were observed before and after stimulation.

Results Significant differences were observed among three stimulation protocols in the changes of stride variability (F = 3.792, P= 0.029), DTC of stride variability (F = 3.412, P= 0.040) and velocity of center of pressure (Vcop) (F = 3.815, P= 0.029). The stride variability (P = 0.047) and Vcop (P = 0.015) were significantly lower and the decrease in DTC of stride variability tended to be significant (P = 0.073) following multi-target tDCS, as compared to sham stimulation. Single-target tDCS significantly decreased the changes of stride variability (P = 0.011), DTC of stride variability (P = 0.014) and Vcop (P = 0.025), as compared to sham stimulation. Compared with single target tDCS, multi-target tDCS reduced the changes of the dual-task cost of the area of center of pressure (P = 0.035). Moreover, no significant difference was observed among the three stimulation protocols in the changes of each measure in the working memory test (P> 0.05).

Conclusion Both multi-target tDCS and single-target tDCS can improve the performance of working memory-postural control dual-task in healthy adults, and compared with single-target tDCS, multi-target tDCS has some advantages in regulating postural control.

Key words: dual-task, postural control, working memory, dorsal lateral prefrontal cortex, primary motor cortex, transcranial direct current stimulation

CLC Number:

R741.05

ZHOU Zhining, ZHOU Rong, XIAO Yanwen, WANG Bowen, LÜ Jiaojiao, LIU Yu. Effect of multi-target transcranial direct current stimulation on performance of working memory-postural control dual-task in healthy adults[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 21-28.

Figures/Tables 5

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References 37

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指标	多靶区tDCS	单靶区tDCS	假刺激	F值	P值
步幅/cm	-0.706±5.874	-0.435±5.010	-1.496±4.089	0.218	0.805
步速/(cm•s^-1)	-1.785±9.769	-2.058±7.951	-3.744±6.062	0.314	0.732
步幅变异性/%	-0.465±0.977^a	-0.748±1.563^c	0.498±1.685	3.792	0.029
步速变异性/%	-0.082±1.023	0.362±3.000	0.751±2.966	0.517	0.599
步幅_{_DTC}/%	0.498±3.767	-0.151±5.002	0.074±3.253	0.123	0.884
步速_{_DCT}/%	-0.412±6.813	-1.481±8.273	-0.435±6.564	0.133	0.876
步幅变异性_{_DTC}/%	-24.263±136.898^b	-54.952±140.630^d	55.199±116.017	3.412	0.040
步速变异性_{_DTC}/%	-8.418±88.656	11.476±139.416	16.113±120.925	0.228	0.797

指标	多靶区tDCS	单靶区tDCS	假刺激	F值	P值
Acop/cm²	-0.031±0.413	0.103±0.413	0.197±0.674	0.931	0.401
Vcop/(cm•s^-1)	-0.812±5.298^a	-0.395±5.241^b	4.235±7.178	3.815	0.029
Acop_{_DTC}/%	-0.076±0.230^c	0.101±0.165	-0.002±0.344	2.366	0.104
Vcop_{_DTC}/%	-0.348±1.081	0.226±0.703	0.273±1.497	1.757	0.183

指标	多靶区tDCS	单靶区tDCS	假刺激	F值	P值
准确率	0.021±0.091	0.003±0.047	0.004±0.046	0.020	0.980
反应时/ms	0.029±0.125	0.001±0.095	-0.057±0.136	1.115	0.335
IES/ms	-0.024±0.050	-0.015±0.038	-0.071±0.040	0.508	0.605

Effect of multi-target transcranial direct current stimulation on performance of working memory-postural control dual-task in healthy adults

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