在线和离线高精度经颅直流电刺激对健康成年人手指运动技能学习效果的随机对照试验

doi:10.3969/j.issn.1006-9771.2024.08.011

Abstract

Abstract:

Objective To investigate the effect of high definition transcranial direct current stimulation (HD-tDCS) at different stimulation timings (online and offline) on finger motor skill learning in healthy adults.

Methods From March to November, 2022, 31 right-handed male participants were recruited from Shenyang Sport University and randomly assigned to three groups, who received online, offline or sham HD-tDCS respectively during the three-day sequential visual isometric pinch task learning process. The daily motor skill learning gains, total motor skill learning gains and speed-accuracy function (SAF) were observed.

Results The daily motor skill learning gains increased in all the groups, and it was the best in the online group (F = 24.692, P < 0.001); the learning gains were better in the online group than in the offline group (t = 4.732, P < 0.001) and the sham group (t = 3.839, P = 0.004) on the third day. The total motor skill learning gains were ranked as the online group = the offline group > the sham group. SAF data indicated that the online group outperformed both the offline and sham groups.

Conclusions HD-tDCS can promote the finger motor skill learning in healthy adults, and online HD-tDCS is more effective.

Key words: repetitive high definition transcranial direct current stimulation, online stimulation, offline stimulation, motor skill learning, randomized controlled trial

CLC Number:

R804.23

NIU Maolin, ZHAO Tan, LIU Xiaoli, GUO Feng. Effect of online and offline high definition transcranial direct current stimulation on finger motor skill learning in healthy adults: a randomized controlled trial[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(8): 957-964.

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References 36

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组别	n	年龄/岁	身高/cm	体质量/kg	体质量指数/(kg•m^-2)
假刺激组	11	22.6±1.3	174.6±2.8	74.9±5.4	24.5±2.2
离线刺激组	11	22.3±1.2	176.0±4.1	78.0±5.3	25.2±2.3
在线刺激组	9	22.6±1.0	177.6±3.1	74.6±4.3	23.6±1.1
F值		0.191	1.970	1.476	1.537
P值		0.828	0.158	0.246	0.233

组别	n	头痛	瘙痒	麻刺	烧灼
假刺激组	11	3	5	3	4
离线刺激组	11	3	3	4	5
在线刺激组	9	2	4	5	3
χ²值		0.085	0.942	1.708	0.346
P值		0.958	0.624	0.426	0.841

组别	n	第1天	第2天	第3天
假刺激组	11	-1.947±0.372	-0.758±0.374	-0.503±0.213
离线刺激组	11	-2.080±0.939	-0.983±0.340	-0.790±0.332
在线刺激组	9	-2.133±1.068	-0.785±0.409	0.064±0.291

效应	平方和	自由度	均方	F值	P值	η_p²值
组别	0.345	2	0.173	0.910	0.424	0.108
时间	26.158	2	13.079	39.743	< 0.001	0.851
组别×时间	1.535	4	0.384	5.101	0.020	0.405

组别	时间	时间	平均值差	P值	95%CI
组别	时间	时间	平均值差	P值	上限	下限
在线刺激组	第1天	第2天	-1.348	< 0.001	-1.894	-0.802
	第1天	第3天	-2.198	< 0.001	-2.856	-1.540
	第2天	第3天	-0.850	< 0.001	-1.198	-0.502
离线刺激组	第1天	第2天	-1.098	0.001	-1.644	-0.552
	第1天	第3天	-1.290	0.001	-1.948	-0.632
	第2天	第3天	-0.192	0.258	-0.539	0.156
假刺激组	第1天	第2天	-1.188	< 0.001	-1.734	-0.642
	第1天	第3天	-1.445	< 0.001	-2.103	-0.787
	第2天	第3天	-0.257	0.137	-0.604	0.091

Effect of online and offline high definition transcranial direct current stimulation on finger motor skill learning in healthy adults: a randomized controlled trial

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组别	n	运动技能学习总量
假刺激组	11	1.74±1.40
离线刺激组	11	3.15±1.50
在线刺激组	9	4.15±1.36

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