胼胝体梗死的康复效果评估：基于功能近红外光谱技术的个案研究

doi:10.3969/j.issn.1006-9771.2025.03.014

Abstract

Abstract:

Objective To report the individualized rehabilitation protocol administered to a patient suffering from corpus callosum injury subsequent to cerebral infarction, manifesting clinically as alien hand syndrome, attention deficits, spatial neglect and gait apraxia; and to emphasize the application of functional near infrared spectroscopy (fNIRS) in the assessment of cerebral activation.

Methods A 54-year-old male with corpus callosum damage following cerebral infarction was assessed by a comprehensive array of neuropsychological assessments, such as Mini-Mental State Examination, Montreal Cognitive Assessment, Loewenstein Occupational Therapy Cognitive Assessment and Wisconsin Card Sorting Test, etc. Based on these assessments, a personalized rehabilitation program was devised, incorporating physical therapy, occupational therapy, task-oriented training, mirror therapy, computer-assisted cognitive training, as well as Schulte's square attention training, bilateral limb coordination training and transcranial magnetic stimulation (TMS). fNIRS was used to evaluate changes in brain activation before and after rehabilitation.

Results After more than a month of comprehensive rehabilitation, the patient experienced significant improvements in Alien hand syndrome, attention deficit and spatial neglect. Gait was normalized, and enhancements were observed in motor function, cognition and activity of daily living. fNIRS analysis revealed favorable alterations in cerebral activation patterns.

Conclusion For the intricate symptoms associated with corpus callosum injury, a multidisciplinary rehabilitation approach, particularly the incorporation of Schulte's square attention training, bilateral coordination exercises and TMS, alongside fNIRS for monitoring cerebral activation, showed significant rehabilitation effects.

Key words: cerebral infarction, corpus callosum, rehabilitation, transcranial magnetic stimulation, functional near infrared spectroscopy

CLC Number:

R743.3

CHEN Yudong, DU Xiaoxia, HUANG Fubiao, YE Changqing, MA Lin, WANG Yunlei, WU Xiaoli. Assessment of rehabilitation of corpus callosum infarction: a case report based on functional near infrared spectroscopy[J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(3): 365-372.

Figures/Tables 5

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References 26

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脑区	时间	通道	SD	左手翻转	右手翻转	双手翻转
左半球	训练前	CH54	S20-D15	-0.0289	0.0342	-0.0094
		CH55	S20-D21	0.0489	0.0300	-0.0016
		CH57	S21-D15	0.0340	-0.0038	-0.0082
	训练后	CH54	S20-D15	-0.0706	0.0148	0.0156
		CH55	S20-D21	-0.0480	0.0124	-0.0119
		CH57	S21-D15	-0.0274	0.0078	0.0237
右半球	训练前	CH30	S12-D12	0.0590	0.0097	0.0046
		CH32	S12-D19	0.0216	-0.0044	0.0104
		CH45	S17-D12	-0.0053	0.0480	0.0014
	训练后	CH30	S12-D12	0.0043	-0.0184	-0.0034
		CH32	S12-D19	0.0123	0.0086	0.0268
		CH45	S17-D12	-0.0371	-0.0231	-0.0126

Assessment of rehabilitation of corpus callosum infarction: a case report based on functional near infrared spectroscopy

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