卒中后中枢性疼痛相关研究的文献计量分析

doi:10.3969/j.issn.1006-9771.2025.09.007

Abstract

Abstract:

Objective To analyze the research status, hotspots and development trends in the field of central post-stroke pain (CPSP).

Methods Relevant literatures up to April 8, 2025 were retrieved from the Web of Science Core Collection database. CiteSpace 6.4.R1 advanced version was used for bibliometric and visualization analysis of publication trends, country/institution/author collaboration networks, keywords and burst terms.

Results A total of 119 publications were included. Researches on CPSP have shown an overall upward trend since 2002, which could be divided into a slow development period (from 2002 to 2015) and a rapid growth period (from 2016 onwards). The number of published papers reached its peak in 2024. China and the United States led in publication volume. Harvard University was the most productive institution, and Asian institutions contributed a significant number of publications. The most prolific author was Gao Ju. The top five keywords by co-occurrence frequency were central post-stroke pain, neuropathic pain, pathophysiology, transcranial magnetic stimulation and motor cortex stimulation. Keyword clustering analysis generated ten clusters, which were integrated into four core research areas: pain types, clinical characteristics and diagnostic techniques, pathophysiological mechanisms, and treatment strategies. The bursting words included spinal cord and molecular expression in recent years; pathophysiology was the most bursting word.

Conclusion In recent years, researches on CPSP are significantly increasing, focusing on pathophysiological mechanisms and intervention strategies. Future studies should strengthen the integration of basic and clinical research, promote multidisciplinary collaboration, and enhance research quality.

Key words: central post-stroke pain, hotspots, bibliometrics

CLC Number:

R743.3

ZHOU Xinyue, YE Ruixue, MA Yaqi, XU Ying, CAO Longyao, WANG Yulong. Researches on central post-stroke pain: a bibliometric analysis[J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(9): 1038-1049.

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References 38

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排名	国家	发文量/n	中心性
1	China	43	0.00
2	USA	21	0.42
3	Japan	14	0.00
4	South Korea	10	0.00
5	Germany	7	0.18

排名	机构	发文量/n	中心性
1	Harvard University	6	0.07
2	Academia Sinica-Taiwan	6	0.00
3	Air Force Medical University	5	0.06
4	Fo Guang University	5	0.00
5	Yeungnam University	4	0.00

排名	作者	国家	发文量/n
1	Gao Ju	中国	5
2	Chen Jun	中国	4
3	Ge Yali	中国	4
4	Huang Tianfeng	中国	3
5	Teixeira, Manoel Jacobsen	巴西	3

排名	期刊	被引频次	中心性
1	Pain	106	0.04
2	Lancet Neurology	76	0.00
3	Stroke	67	0.02
4	Neurology	66	0.07
5	Brain	63	0.07

排名	第一作者	文献题目	期刊	频次
1	Choi, Hanwool Ryan	Pharmacotherapy to manage central post-stroke pain	CNS Drugs, 2021, 35 (2): 151-160.	15
2	Liampas, Andreas	Prevalence and management challenges in central post-stroke neuropathic pain: a systematic review and meta-analysis	Advances in Therapy, 2020, 37 (7): 3278-3291.	15
3	Hanada, Tomoko	Development and pharmacological verification of a new mouse model of central post-stroke pain	Neuroscience Research, 2013, 78: 72-80.	8
4	Ramger, Benjamin Curtis	Effects of non-invasive brain stimulation on clinical pain intensity and Experimental pain sensitivity among individuals with central post-stroke pain: a systematic review	Journal of Pain Research, 2019, 12: 3319-3329.	8
5	Tianfeng Huang	Fgr contributes to hemorrhage-induced thalamic pain by activating NF-κB/ERK1/2 pathways	JCI Insight, 2020, 5 (20): e139987.	7

Researches on central post-stroke pain: a bibliometric analysis

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排名	关键词	频次	中心性
1	central poststroke pain	70	0.20
2	neuropathic pain	50	0.28
3	pathophysiology	19	0.05
4	transcranial magnetic stimulation	19	0.10
5	motor cortex stimulation	19	0.12
6	stroke	16	0.06
7	post stroke pain	13	0.07
8	animal model	13	0.18
9	activation	12	0.28
10	deep brain stimulation	10	0.18

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