《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2005, Vol. 11 ›› Issue (05): 388-389.
• 临床研究 • Previous Articles Next Articles
WANG Li-xin, WANG Bao-guo
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Abstract: ObjectiveTo investigate the effects of intravenous fentanyl combined with scalp nerve block with ropivacaine on the hemodynamic response to skin incision during craniotomy.Methods43 ASA Ⅰ~Ⅱ patients scheduled for selective frontotemporal craniotomy were randomly assigned into 3 groups: the isoflurane group(group I,n=14), the fentanyl group (group F, n=15) and the fentanyl-ropivacaine group (group B, n=14 ).Anesthetic induction was performed with IV remifentanil 2 μg/kg, propofol 2 mg/kg, and vecuronium 0.1mg/kg. Group F received fentanyl 3 μg/kg 5 min before skin incision .Group B received the same doses of fentanyl prior to skin incision as well as scalp nerve block with 1% ropivacaine before induction. Anesthesia was maintained with isoflurane. The "up and down" method was used to determine MAC-BAR in each group.ResultsThe end-tidal isoflurane concentration blocking sympathetic response to incision in group I, F and B were 2.0%,1.8%,1.0% respectively.The MAC-BAR of group I, F and B were 1.7 MAC,1.55 MAC,0.8 MAC respectively. The end-tidal isoflurane concentration blocking sympathetic response to incision and MAC-BAR of group B decreased obviously compared with that of group I and F(P<0.05).ConclusionIntravenous fentanyl combined with scalp nerve block with ropivacaine can successfully reduce the hemodynamic response to skin incision.
Key words: peripheric nerve block, fentanyl, craniotomy, isoflurane, end-tidal isoflurane concentration
WANG Li-xin;WANG Bao-guo. Scalp nerve block combined with intravenous fentanyl decrease MAC-BAR [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2005, 11(05): 388-389.
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