Abstract: Objective To explore the influence of psycho-behavioral intervention on psychological status and quality of life in patients with gastroesophageal reflux disease (GERD). Methods 62 patients with GERD were divided into intervention group (n=30) and control group (n=32). Both groups received routine treatment, and the intervention group received psychological care applying cognitive, emotional,behavioral, social support intervention in addition. They were assessed with Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and Generic Quality of Life Inventory (GQOLI) before and 6 weeks after intervention. Results The scores of SAS, SDS, and GQOLI (all the dimensions and total) improved in the intervention group compared with the control group after intervention (P<0.05). Conclusion Psycho-behavioral intervention can reduce the anxiety and depression, and improve the quality of life for patients with GERD.

Key words: gastroesophageal reflux disease, psycho-behavioral intervention, anxiety, depression, quality of life