Abstract: Objective To investigate the risk factors of recurrent ischemic stroke, and evaluate the severity and short- term outcome. Methods From March, 2014 to March, 2015, 238 patients with recurrent ischemic stroke and 378 patients with initial ischemic stroke matched with gender and age were enrolled. The clinical data of two groups were compared and the non-conditional Logistic regression model was made to analysis the risk factors of recurrent ischemic stroke. The National Institute of Health Stroke Scale (NIHSS) score as admission and discharge, and the neural function improvement rate of two groups were compared. Results The incidences of leukoarailsis (χ2= 8.666), hypertension (χ2=8.189), smoking (χ2=6.973) and alcohol consumption (χ2=4.722) were higher in the recurrent group than in the primary group (P<0.05). Logistic regression analysis showed that leukoarailsis (OR=1.690, 95%CI: 1.198~2.384, P=0.003), hypertension (OR= 1.715, 95%CI: 1.135~2.592, P=0.010) and smoking (OR=1.896, 95%CI: 1.233~2.915, P=0.004) were the independent risk factors of recurrent ischemic stroke. The NIHSS scores as admission and discharge were significantly higher (t=-3.645, t=-4.675, P<0.001), and the neural function improvement rate was lower (t=2.643, P<0.01) in the recurrent group than in the primary group. Conclusion Hypertension, leukoarailsis and smoking are independent risk factors for recurrent ischemic stroke. Recurrent ischemic stroke is more serious than initial ischemic stroke, and the short-term neural function recovers more slowly.

Key words: ischemic stroke, recurrent, risk factor, National Institute of Health Stroke Scale, outcome