Abstract: Objective To explore the effect of Occupational Therapy in Group on cognitive function of children with March to cerebral palsy, and to observe the evaluation results of P300 of event-related potentials on cognitive function. Methods 40 children with spastic cerebral palsy from March to September, 2015, were divided into control group (n=20) and observation group (n=20). Both groups received routine rehabilitation training, and the observation group received Occupational Therapy in Group additionally, for 3 months. They were assessed with Wechsler Preschool and Primary Scale of Intelligence (WPPSI) and P300 of event-related potentials before and after treatment. Results The latency of P300 shortened after treatment (t>7.778, P<0.001), and the amplitude of P300 was larger after treatment (t>5.808, P< 0.001) in both groups, especially in the observation group (t>0.461, P<0.05). The score of WPPSI increased after treatment in both groups (t>5.944, P<0.001), and was higher in the observation group than in the control group (t=-3.472, P=0.001). Conclusion Occupational Therapy in Group could further improve the cognitive function of children with spastic cerebral palsy. P300 can be used as an assessment tool for cognitive function.

Key words: cerebral palsy, occupational therapy in group, cognitive function, event-related potentials