头针结合计算机辅助训练对脑卒中后记忆障碍的效果

doi:10.3969/j.issn.1006-9771.2025.07.014

Abstract

Abstract:

Objective To observe the effect of scalp acupuncture points including Shenting (GV24), Benshen (GB13) and Sishencong (EX-HN1) combined with computer-assisted training on memory impairment after stroke.

Methods From May, 2023 to December, 2024, 62 patients with post-stroke memory dysfunction who received rehabilitation treatment in Beijing Bo'ai Hospital were selected and divided into control group (n = 31) and observation group (n = 31) randomly. Both groups received conventional treatment and computer-assisted training, while the observation group received additional scalp acupuncture treatment, for four weeks. They were evaluated with Montreal Cognitive Assessment (MoCA), auditory memory span, and modified Barthel Index (MBI) before and after treatment.

Results No adverse reaction occured during treatment. After treatment, the total score of MoCA and the memory dimension score, and auditory memory span score improved in both groups (|t| > 3.838, P < 0.001), and the d-value was more in the observation group than in the control group (|t| > 2.160, P < 0.05); the score of MBI improved in both groups (|t| >7.471, P < 0.001), however, there was no significant difference between two groups (P > 0.05).

Conclusion Computer-assisted training could significantly improve the cognitive function of patients with post-stroke memory dysfunction, especially the memory function, and is more effective while combining with scalp acupuncture.

Key words: stroke, scalp acupuncture, computer-assisted training, memory impairment, auditory memory span

CLC Number:

R743.3

LIU Lanqun, LI Yanli, LIANG Jiaqi, CHEN Shuang, LIU Huilin. Effect of scalp acupuncture combined with computer-assisted training on memory impairment after stroke[J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(7): 862-868.

Figures/Tables 4

Table 1

Table 2

Comparison of the total scores of MoCA and memory scores between two groups pre and post-treatment"

变量	组别	n	测试	$x - ± s$	t值	P值
MoCA	对照组	31	前测	14.87±5.43	-17.600	< 0.001
			后测	17.81±5.80
	观察组	31	前测	14.65±5.72	-12.898	< 0.001
			后测	19.42±5.26
	治疗前两组均值差			-0.23±8.56	0.159	0.874
	治疗后两组均值差			1.61±8.54	-1.147	0.256
	对照组增加值			2.94±0.93	-4.529	< 0.001
	观察组增加值			4.77±2.06
记忆分值	对照组	31	前测	1.39±5.43	-5.043	< 0.001
			后测	1.94±1.44
	观察组	31	前测	1.32±1.49	-7.019	< 0.001
			后测	2.42±1.36
	治疗前两组均值差			-0.10±2.33	0.265	0.792
	治疗后两组均值差			0.48±1.98	-1.362	0.178
	对照组增加值			0.52±0.57	-3.108	0.003
	观察组增加值			1.10±0.87

Table 2

Table 3

Comparison of auditory memory span (forward and reverse) between two groups pre and post-treatment"

变量	组别	n	测试	$x - ± s$	t值	P值
听觉广度(正向)	对照组	31	前测	5.13±1.91	-5.043	< 0.001
			后测	5.65±1.91
	观察组	31	前测	5.06±1.79	-3.838	< 0.001
			后测	6.32±1.94
	治疗前两组均值差			-0.06±2.42	0.137	0.891
	治疗后两组均值差			0.68±3.24	-1.387	0.171
	对照组增加值			0.52±0.57	-2.160	0.038
	观察组增加值			1.26±1.83
听觉广度(反向)	对照组	31	前测	2.58±1.31	-4.728	< 0.001
			后测	3.06±1.15
	观察组	31	前测	2.55±1.23	-5.780	< 0.001
			后测	3.45±1.36
	治疗前两组均值差			-0.03±1.91	0.100	0.921
	治疗后两组均值差			0.39±1.98	-1.208	0.232
	对照组增加值			0.48±0.57	-2.245	0.028
	观察组增加值			0.90±0.87

Table 3

Table 4

Comparison of MBI scores between two groups pre and post-treatment"

组别	n	测试	$x - ± s$	t值	P值
对照组	31	前测	37.26±6.69	-7.471	< 0.001
		后测	45.48±8.88
观察组	31	前测	37.42±6.31	-11.333	< 0.001
		后测	48.39±10.20
治疗前两组均值差			0.16±9.17	-0.098	0.923
治疗后两组均值差			2.90±12.03	-1.195	0.237
对照组增加值			8.23±6.13	-1.871	0.066
观察组增加值			10.97±5.39

Table 4

References 34

[1]	蹇秋枫, 徐荣华, 姚倩, 等. 中国老年脑卒中患者认知障碍患病率和影响因素的Meta分析[J]. 中国全科医学, 2023, 26(32): 4070-4079, 4088. doi: 10.12114/j.issn.1007-9572.2023.0212
	JIAN Q F, XU R H, YAO Q, et al. A meta-analysis of the prevalence and influencing factors of post-stroke cognitive impairment in Chinese elderly patients[J]. Chin Gener Pract, 2023, 26(32): 4070-4079, 4088.
[2]	王拥军, 李子孝, 谷鸿秋, 等. 中国卒中报告2019(中文版)(3)[J]. 中国卒中杂志, 2020, 15(12): 1251-1263.
	WANG Y J, LI Z X, GU H Q, et al. China Stroke Report 2019 (Chinese version) (3)[J]. Chin J Stroke, 2020, 15(12): 1251-1263.
[3]	WANG Y J, LI Z X, GU H Q, et al. China stroke statistics 2019: a report from the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations[J]. Stroke Vasc Neurol, 2020, 5(3): 211-239.
[4]	CAF K, RAKUSA M. Self-awareness of acute post-stroke cognitive decline[J]. Alzheimer Dement, 2025, 20(S7): e093100-e093100.
[5]	范舒涵, 牛星阳, 古锦敏, 等. 脑卒中后汉语失语症患者的言语和空间工作记忆障碍[J]. 中山大学学报(医学科学), 2021, 42(5): 738-745.
	FAN S H, NIU X Y, GU J M, et al. Verbal and spatial working memory impairments in Chinese speakers with post-stroke aphasia[J]. J Sun Yat-Sen Univ (Med Sci), 2021, 42(5): 738-745.
[6]	WANG B, ZHONG L, QIAO P, et al. Clinical efficacy and safety of nicergoline combined with oxiracetam in the treatment of vascular cognitive impairment[J]. Pak J Pharm Sci, 2020, 33(1): 417-422.
[7]	汪凯, 董强, 郁金泰, 等. 卒中后认知障碍管理专家共识2021[J]. 中国卒中杂志, 2021, 16(4): 376-389.
	WANG K, DONG Q, YU J T, et al. Expert consensus on the management of post-stroke cognitive impairment 2021[J]. Chin J Stroke, 2021, 16(4): 376-389.
[8]	DAMODARAN T, CHEAH P S, MURUGAIYAH V, et al. The nootropic and anticholinesterase activities of clitoria ternatea Linn. root extract: potential treatment for cognitive decline[J]. Neurochem Int, 2020, 139: 104785.
[9]	LIU L P, LI Z X, ZHOU H Y, et al. Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update[J]. Stroke Vasc Neurol, 2023, 8(6): e3. doi: 10.1136/svn-2023-002998 pmid: 38158224
[10]	WU J, MA Y, REN Z. Rehabilitative effects of virtual reality technology for mild cognitive impairment: a systematic review with meta-analysis[J]. Front Psychol, 2020, 11: 1811. doi: 10.3389/fpsyg.2020.01811 pmid: 33101098
[11]	宋宛宸, 邓颖, 黄山, 等. 脑卒中后认知障碍患者非药物治疗的研究进展[J]. 中西医结合护理, 2024, 10(3): 21-26.
	SONG W C, DENG Y, HUANG S, et al. Research progress of non-drug therapy for post-stroke patients with cognitive impairment[J]. Chin J Integr Nurs, 2024, 10(3): 21-26.
[12]	甘婷, 汤富友, 李静, 等. 计算机辅助认知训练对脑卒中患者认知功能影响的Meta分析[J]. 中国医药科学, 2021, 11(23): 61-65.
	GAN T, TANG F Y, LI J, et al. Meta-analysis of the effect of computer-assisted cognitive training on cognitive function of stroke patients[J]. Chin Med Pharm, 2021, 11(23): 61-65.
[13]	FETTA J, STARKWEATHER A, GILL J M. Computer-based cognitive rehabilitation interventions for traumatic brain injury: a critical review of the literature[J]. J Neurosci Nurs, 2017, 49(4): 235-240. doi: 10.1097/JNN.0000000000000298 pmid: 28661947
[14]	阮娟娟, 魏霞, 孔艳芳, 等. 头针带针康复疗法治疗缺血性脑卒中后认知功能障碍的临床疗效观察[J]. 中医药信息, 2024, 41(6): 50-54.
	RUAN J J, WEI X, KONG Y F, et al. Clinical observation of therapeutic effect of scalp acupuncture with long time needle retention rehabilitation on cognitive impairment after ischemic stroke[J]. Inform TCM, 2024, 41(6): 50-54.
[15]	玄红, 王恩龙. 头针治疗脑卒中后认知功能障碍研究进展[J]. [网络首发]. 实用中医内科杂志, 2023. http://kns.cnki.net/kcms/detail/21.1187.R.20231030.1656.004.html.
	XUAN H, WANG E L. Research Progress of Scalp Acupuncture Therapy for Post-stroke Cognitive Impairment[J]. [ahead of print]. J Prac Trad Chin Internal Med, 2023. http://kns.cnki.net/kcms/detail/21.1187.R.20231030.1656.004.html.
[16]	陈小露, 赵荣, 任泽琴. 针灸结合现代康复治疗卒中认知障碍研究进展[J]. 云南中医药大学学报, 2024, 47(4): 90-97.
	CHEN X L, ZHAO R, REN Z Q. Research progress of acupuncture combined with modern rehabilitation in the treatment of cognitive impairment after stroke[J]. J Yunnan Univ Chin Med, 2024, 47(4): 90-97.
[17]	李光硕, 赵性泉. «中国急性缺血性卒中诊治指南2023»解读[J]. 中国卒中杂志, 2024, 19(8): 956-961.
	LI G S, ZHAO X Q. Interpretation of the Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2023[J]. Chin J Stroke, 2024, 19(8): 956-961.
[18]	邓里娜, 吴波. «中国脑出血诊治指南2019»更新要点及解读[J]. 心脑血管病防治, 2021, 21(1): 13-17.
[19]	LE B A. Cognitive impairment after stroke[J]. Lab Animal, 2019, 48(6): 165. doi: 10.1038/s41684-019-0323-9
[20]	刘兰群, 李惠兰, 陈之罡, 等. 电针头部"神"穴对脑卒中后认知功能障碍的效果[J]. 中国康复理论与实践, 2015, 21(5): 575-578.
	LIU L Q, LI H L, CHEN Z G, et al. Effects of electroacupuncture on head Shen-acupoints on cognitive impairment after stroke[J]. Chin J Rehabil Theory Pract, 2015, 21(5): 575-578.
[21]	刘兰群, 李惠兰, 徐基民. 电针治疗脑卒中后记忆功能障碍临床研究[J]. 中国中医急症, 2015, 24(5): 775-777.
	LIU L Q, LI H L, XU J M. Clinical study of electroacupuncture on memory dysfunction after stroke[J]. J Emerg Tradit Chin Med, 2015, 24(5): 775-777.
[22]	中华医学会神经病学分会神经康复学组, 中华医学会神经病学分会脑血管病学组, 卫生部脑卒中筛查与防治工程委员会办公室. 中国脑卒中康复治疗指南(2011完全版)[J]. 中国康复理论与实践, 2012, 18(4): 301-318.
[23]	恽晓平. 基于研究证据的认知康复[J]. 中国康复理论与实践, 2011, 17(6): 512-514.
	YUN X P. Evidence-based cognition rehabilitation[J]. Chin J Rehabil Theory Pract, 2011, 17(6): 512-514.
[24]	孟繁媛, 陈茉弦, 唐欣, 等. 本土化计算机辅助训练对脑外伤后记忆障碍的疗效观察[J]. 中国康复, 2020, 35(12): 629-632.
	MENG F Y, CHEN M X, TANG X, et al. Therapeutic effect of developed computer-assisted software for memory function intraumaticbrain injury patient[J]. Chin J Rehabil, 2020, 35(12): 629-632.
[25]	周季桦, 高林, 赵晓庆, 等. 认知功能障碍康复评估方法的研究进展[J]. 中医康复, 2025, 2(1): 76-80.
	ZHOU J H, GAO L, ZHAO X Q, et al. Research progress of rehabilitation assessment methods for cognitive dysfunction[J]. Rehabil Trad Chin Med, 2025, 2(1): 76-80.
[26]	RUNDEK T, TOLEA M, ARIKO T, et al. Vascular cognitive impairment (VCI)[J]. Neurotherapeutics, 2022, 19(1): 68-88.
[27]	张卓. 通督调神针刺法治疗卒中后认知障碍非痴呆的临床研究[D]. 广州: 广州中医药大学, 2023.
	ZHANG Z. Study on acupuncture therapy of dredging governor vessel for regulating mentality in post-stroke cognitive impairment non-dementia[D]. Guangzhou: Guangzhou University of Chinese Medicine, 2023.
[28]	罗春洪. 升阳通督调神针法联合电针治疗脑卒中后认知功能障碍的临床研究[D]. 昆明: 云南中医药大学, 2023.
	LUO C H. Clinical study of acupuncture by Shengyang Tongdu Tiaoshen combined with electroacupuncture in post-stroke cognitive impairment[D]. Kunming: Yunnan University of Chinese Medicine, 2023.
[29]	王飞, 高珊, 杨林. 针刺联合认知训练治疗缺血性卒中后认知功能障碍疗效观察[J]. 上海针灸杂志, 2021, 40(7): 795-800.
	WANG F, GAO S, YANG L. Efficacy observation of acupuncture combined with cognitive training for cognitive impairment after ischemic stroke[J]. Shanghai J Acu-mox, 2021, 40(7): 795-800.
[30]	陈振兴. 头针丛刺结合电针治疗脑卒中后认知障碍的临床疗效观察[D]. 长春: 长春中医药大学, 2023.
	CHEN Z X. Clinical observation on treatment of cognitive impairment after stroke with scalp acupuncture combined with electroacupuncture[D]. Changchun: Changchun University of Chinese Medicine, 2023.
[31]	孙兴华. 基于内质网应激头穴丛刺对血管性痴呆大鼠保护机制研究[R]. 哈尔滨: 黑龙江中医药大学附属第二医院, 2021.
[32]	魏高峡, 盖力锟, 林萱. 运动认知神经科学研究(2012-2022):10年回顾与未来展望[J]. 科学通报, 2024, 69(24): 3492-3514.
	WEI G X, GE L K, LIN X. A decade of progress in sports and exercise neuroscience from 2012 to 2022: A review and perspectives[J]. Chin Sci Bull, 2024, 69: 3492-3514.
[33]	YUE C, YU Q, ZHANG Y, et al. Regular Tai Chi practice is associated with improved memory as well as structural and functional alterations of the hippocampus in the elderly[J]. Front Aging Neurosci, 2020, 12: 586770.
[34]	王春旭, 马静毅, 顾超. 非痴呆型血管性认知障碍中西医治疗进展[J]. 山东中医药大学学报, 2023, 47(3): 370-375.
	WANG C X, MA J Y, GU C. Treatment progress of traditional Chinese and western medicine for vascular cognitive impairment no dementia[J]. J Shandong Univ Trad Chin Med, 2023, 47(3): 370-375.

组别	n	性别/n		年龄/岁	病程/周	脑卒中类型/n		文化程度/n
组别	n	男	女	年龄/岁	病程/周	出血	梗死	大学/大专及以上	高中/中专	初中及以下
对照组	31	16	15	57.52±9.26	11.0(8.5,15.0)	11	20	9	10	12
观察组	31	18	13	58.61±8.83	10.5(8.5,12.0)	13	18	8	12	11
χ²/t/Z值		0.261		0.477	-0.474	0.272		0.284
P值		0.610		0.635	0.635	0.602		0.868

Effect of scalp acupuncture combined with computer-assisted training on memory impairment after stroke

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 4

References 34

Related Articles 15

Metrics

Comments

Recommended 0

[1]	SUN Wanting, YASEN Ailipinai, GONG Xiang, XIAO Yue, GAN Zhaodan, LIU Mingjie, ZENG Lanting, MA Shuyue, LU Jun, XU Guangxu. Effect of high-frequency repetitive transcranial magnetic stimulation on upper limb function of stroke patients based on motor sequence learning [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(7): 812-821.
[2]	SHAN Lei, LIU Ying, ZHANG Xin, CHI Qianqian, ZHU Xiaomin. Effect of accelerated intermittent theta burst stimulation on post-stroke depression [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(7): 822-829.
[3]	LIU Xuan, GAO Ling, CHU Fengming, CHEN Jie, ZHANG Ming. Effect of brain-computer interface combined with upper limb rehabilitation robot on upper limb function of stroke patients [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(6): 703-710.
[4]	FU Guojun, YU Xiufang, LÜ Xin, JI Lu, LIU Huaqing. Effect of composite electromagnetic stimulation combined with chin tuck against resistance on post-stroke patients with dysphagia [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(6): 721-728.
[5]	LIANG Dan, WANG Weining, LI Ce, WU Yue, XU Shu, XIE Hongyu, WU Yi, ZHU Yulian. Effect of synchronous brain bionic electrical stimulation in hyperbaric oxygen chamber on stroke-related sleep disorders [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(5): 497-504.
[6]	BAI Min, CAO Lihua, YE Ziqi, ZHOU Dingjie, LI Xueping. Effect of electromyographic perception-assisted robotic training combined with paired association stimulation on upper limb function in hemiplegic patients after stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(5): 505-512.
[7]	ZOU Congcong, WANG Xiaojun, MA Jinrong, LU Shangbo, DING Yong, WANG Hani, SONG Jianfei. Effect of transcutaneous auricular vagus nerve stimulation combined with dual-task training on upper limb function in patients with ischemic stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(5): 513-519.
[8]	SHI Bin, XU Ning, ZHOU Guangxue. Application of mirror therapy in motor function rehabilitation for stroke: a bibliometric analysis from 2005 to 2024 [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(5): 561-572.
[9]	CHEN Mengye, QU Qingming, ZHU Jie, CHEN Xianggui, JIA Jie. Characteristics of cardiorespiratory fitness in patients with post-stroke hemiplegia based on cardiopulmonary exercise testing [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(4): 441-447.
[10]	LI Xinlei, WEI Wei, SONG Jian, ZHAO Yuqing, KONG Weicheng, CAI Jiayu, SHI Haoran, XUE Xiehua. Application of resting-state electroencephalography in assessment of upper limb motor function of stroke patients [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(4): 448-457.
[11]	LIU Pengcheng, QU Mengjian, LONG Liping, WANG Yalin, YANG Mingzhu, LIU Peiyong, ZHOU Jun, LIU Jing. Effect of pneumatic and electric hand training system with multiple sensory stimulation modalities combined with low-frequency repetitive transcranial magnetic stimulation on hand movement and tactile pressure sensation in patients with stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(4): 458-465.
[12]	SU Panpan, YE Peng, LU Qian, HE Chuan, LU Xiao. Effect of visual deprivation training combined with proprioceptive training on balance in hemiplegic patients after stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(3): 254-263.
[13]	LIN Changsheng, CAO Yu, WANG Tong, DAI Wenjun, HOU Hong, HU Cuiqin, BAO Shilei, PANG Sufang. Effect of closed-chain exercise training on hemiplegic shoulder pain and shoulder joint stability in stroke patients: a study with ultrasound [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(3): 264-273.
[14]	WANG Xiaojun, WANG Hani, YU Hong, LI Yuanmei, ZHOU Yuda. Effect of high-definition transcranial direct current stimulation combined with upper limb robot on upper limb dysfunction after ischemic stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(2): 218-224.
[15]	MA Wenwen, WEN Yanzheng, Manripati ROZI, CUI Boya, Suyinqimei . Effect of healthy side tilt training on balance function in patients with Pusher syndrome after stroke [J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(2): 225-230.