Abstract: ObjectiveTo observe the effect of early rehabilitation on patients with severe closed traumatic brain injury in intensive care unite (ICU).Methods118 patients with severe closed traumatic brain injury were divided randomly into the treatment group and control group with 59 cases in each group. The patients of control group recieved respiration rehabilitation, bedsore prevention and urinary system nursing; while the patients of treatment group added with motor and cognitive rehabilitation. Scores of Glasgow coma scale (GCS), Fugl-Mayer assessment (FMA), mini-mental status examination (MMSE), disability rating scale (DRS) and activities of daily living (ADL) of all patients were recorded before and after treatment.ResultsThe scores of GCS, FMA (upper limbs), ADL and DRS of the treatment group patients were significantly difference with that of the control group after treatment (P<0.05). The MMSE scores of two groups had no significantly difference after treatment (P>0.05).ConclusionEarly rehabilitation on the patients of severe closed traumatic brain injury in ICU can improve brain function and reduce the disability rating scale. The improvement of cognitive ability is not obviously in a shot period.

Key words: brain injury, rehabilitation, never function