Abstract: Objective To investigate the correlation of subtypes of the lymphocytes with metabolic syndrome in the aged.Methods 955 aged male and 150 aged female were recruited to a cross-sectional case-control study.CD₃+,CD₄,CD₈+,CD₁₉+,NK cell was measured with flow cytometry.ResultsCD₃+,CD₁₉+,NK cells showed no difference in cases and in controls.CD₄+/CD₈+ ratio declined in subjects with metabolic syndrome,and the ratio declined further with the more criteria.The analysis of multiple analysis regression showed that metabolic syndrome depressed CD₄+/CD₈+ ratio in the aged.Conclusion Metabolic syndrome was correlated with the disorder of immunity.

Key words: metabolic syndrome, immunity, lymphocyte