《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2008, Vol. 14 ›› Issue (06): 557-559.
• 临床研究 • Previous Articles Next Articles
GONG Yan, JIN Mei-ling, REN Tao, et al
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Abstract: Objective To investigate the relationship between tumor necrosis factor-alpha (TNF-α) and development of chronic obstructive pulmonary disease (COPD).Methods COPD patients and controls were divided into three groups: COPD group (n=66), smoker control group (n=42) and health control group (n=23). COPD group was further divided into the serious group (n=23) and non-serious group (n=43). The concentration of TNF-α of all cases was detected by human Th1/Th2 cytokine kit.Results The concentration of TNF-α in the COPD group was significantly higher than that of the smoker and healthy groups ( P<0.01). Furthermore, compared to non-serious COPD group, the concentration of TNF-α was higher in the serious COPD group ( P<0.05).Conclusion The concentration of TNF-α might be related with the pathogenesis and development of COPD.
Key words: chronic obstructive pulmonary disease (COPD), tumor necrosis factor-alpha (TNF-α), smoking
GONG Yan;JIN Mei-ling;REN Tao;et al. Relationship between Tumor Necrosis Factor-alpha and Smoking-related Chronic Obstructive Pulmonary Disease [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2008, 14(06): 557-559.
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