《Chinese Journal of Rehabilitation Theory and Practice》 ›› 1999, Vol. 5 ›› Issue (03): 106-109.

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Studies on biodegradable polymers in vitro degradation of poly(DL lactide)films

Zhang Ying,Piao Dongxu,Mao Lijiang   

  1. Chinese Journal of Rehabilitation Theory & Practice.-1999,5(3):106~109
  • Received:1998-12-07 Published:1999-09-25 Online:1999-09-25

Abstract: In the paper,in vitro degradation of DL polylactic acid (PDLLA) film was studied.Regulation and tendency of degradation were showed by molecular weight regulator and monomer ration mass lossing.Degradation mechanism was discussed in light.It was thought that degradation of PDLLA in vitro was a simple hydrolysis reaction.The hydrolysis reaction was self catalytic reaction caused by terminal carboxyl group.

Key words: PDLLA film, degradation, polylactic acid, lactic acid, molecular weight, regulator and monomer ration, mass lossing.