运动前皮质阳极经颅直流电刺激对重症脑卒中患者上肢运动功能的效果

doi:10.3969/j.issn.1006-9771.2023.11.011

Abstract

Abstract:

Objective To explore the effect of anodal transcranial direct current stimulation (atDCS) on premotor cortex (PMC) on upper limb motor function in patients with severe stroke.

Methods From June, 2021 to December, 2022, 60 patients with severe stroke in Zhejiang Provincial People's Hospital were randomly divided into control group (n = 20), primary motor cortex (M1) group (n = 20) and PMC group (n = 20). All the groups accepted routine rehabilitation treatment, while the control group accepted atDCS pseudo stimulation to the focus side PMC, M1 group accepted atDCS to the focus side M1, and PMC group accepted atDCS to the focus side PMC, for six weeks. Fugl-Meyer Assessment-Upper Extremities (FMA-UE), Wolf Motor Function Test (WMFT), the surface electromyography root mean square (RMS) ratio of affected/unaffected side of triceps and extensor carpus were used to evaluate the efficacy before and after treatment.

Results After treatment, the scores of FMA-UE and WMFT, and RMS ratio of triceps and extensor carpus significantly increased in all the groups (|t| > 2.458, P < 0.05), and were better in PMC group than in the other two groups (F > 4.084, P< 0.05).

Conclusion atDCS on PMC could improve the overall function of upper limb in patients with severe stroke.

Key words: stroke, upper limbs, motor function, transcranial direct current stimulation, premotor cortex

CLC Number:

R743.3

SUN Fengbao, ZHANG Xiaofeng, JIN Zhenhua, CHEN Tiantian. Effect of anodal transcranial direct current stimulation on premotor cortex on upper limb motor function in patients with severe stroke[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(11): 1333-1338.

Figures/Tables 5

References 36

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组别	n	性别(男/女)/n	年龄/岁	病程/d	NIHSS评分	卒中性质(梗死/出血)/n	偏瘫侧(左/右)/n
对照组	20	11/9	61.35±9.82	38.10±4.75	17.15±2.06	9/11	10/10
M1组	20	13/7	59.90±10.80	39.25±4.60	16.40±2.60	10/10	9/11
PMC组	20	14/6	62.15±9.40	37.95±5.07	16.65±2.30	12/8	7/13
F/χ²值		1.005	0.259	0.437	0.536	0.934	1.765
P值		0.605	0.773	0.648	0.588	0.627	0.414

组别	n	治疗前	治疗后	t值	P值
对照组	20	12.95±2.84	16.15±4.17	-2.862	0.010
M1组	20	14.15±2.54	16.60±3.07^a	-3.143	0.005
PMC组	20	13.60±3.05	19.55±2.96^b,c	-8.529	< 0.001
F值		0.909	5.749
P值		0.409	0.005

组别	n	治疗前	治疗后	t值	P值
对照组	20	19.75±3.91	22.50±5.25	-2.458	0.024
M1组	20	20.35±3.84	23.15±3.79^a	-2.685	0.015
PMC组	20	20.70±3.67	27.15±4.48^b,c	-10.443	< 0.001
F值		0.319	6.146
P值		0.728	0.004

组别	n	治疗前	治疗后	t值	P值
对照组	20	0.07±0.03	0.09±0.05	-3.108	0.006
M1组	20	0.07±0.03	0.10±0.03^a	-4.190	< 0.001
PMC组	20	0.07±0.02	0.13±0.04^b,c	-12.096	< 0.001
F值		0.161	4.084
P值		0.851	0.022

组别	n	治疗前	治疗后	t值	P值
对照组	20	0.07±0.03	0.11±0.05	-4.155	0.001
M1组	20	0.08±0.04	0.12±0.06^a	-4.166	0.001
PMC组	20	0.08±0.04	0.15±0.05^b,c	-17.260	< 0.001
F值		0.432	4.265
P值		0.651	0.019

Effect of anodal transcranial direct current stimulation on premotor cortex on upper limb motor function in patients with severe stroke

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