功能性电刺激手摇车对脑卒中患者脑网络功能连接的功能性近红外光谱研究

doi:10.3969/j.issn.1006-9771.2025.10.009

Abstract

Abstract:

Objective To explore the potential central mechanisms of functional electrical stimulation (FES) hand cycling in promoting upper limb motor recovery after stroke.
Methods A total of 35 stroke patients hospitalized in the Rehabilitation Center of Changzhou De'an Hospital from May, 2023 to December, 2024 were enrolled. They sequentially completed 10-minute FES hand cycling and 10-minute sham stimulation (simple hand cycling) tasks. The task order was randomized via dice rolling. Functional near-infrared spectroscopy (fNIRS) was used to monitor real-time cerebral hemodynamic changes during both tasks to calculate the overall functional connectivity (FC) strength and the FC strength within regions of interest.
Results The overall FC strength was higher during the FES hand cycling task than during the sham task (t = 2.591, P < 0.05), as well as FC between the ipsilateral primary motor cortex (iM1) and ipsilateral somatosensory association cortex (iSAC), iM1 and contralateral somatosensory association cortex (cSAC), ipsilateral pre-motor and supplementary motor cortex (iPMC) and iSAC, iPMC and cSAC, iPMC and ipsilateral primary somatosensory cortex (iS1), iPMC and iM1, and contralateral pre-motor and supplementary motor cortex (cPMC) and iSAC (P_FDR < 0.05).
Conclusion FES hand cycling can promote the cortical function remodeling between cerebral hemispheres and the affected hemisphere, to integrate sensory-motor function.

Key words: stroke, upper limb, motor function, functional electrical stimulation hand cycling, functional near-infrared spectroscopy, functional connection, cortical function remodeling

CLC Number:

R743.3

XU Sheng, ZHANG Min, YANG Qingqing, WANG Qinglei, GENG Ayan, WANG Tong, GUO Chuan. Effect of functional electrical stimulation hand cycling on functional connection of brain networks in stroke patients: a study based on functional near-infrared spectroscopy[J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(10): 1181-1187.

Figures/Tables 4

References 38

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项目	量值
性别(男/女)/n	24/11
年龄/岁	58.94±9.81
偏瘫侧(左/右)/n	18/17
卒中类型(出血/梗死) /n	12/23
病程/d	46(28, 87)
BMI/(kg·m^-2)	24.61±2.77
MMSE	26.17±1.36
Fugl-Meyer评定量表上肢部分	9(6, 19)
改良Bathel指数	41.43±19.42

任务	n	$\bar{x}±s$	t值	P值
FES手摇车	35	0.731±0.243	2.591	0.012
单纯手摇车	35	0.573±0.292	2.591	0.012

Effect of functional electrical stimulation hand cycling on functional connection of brain networks in stroke patients: a study based on functional near-infrared spectroscopy

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