Objective To investigate the effect of telerehabilitation on memory disorders. Methods From August, 2010 to April, 2015, 81 patients with memory disorders were randomized into control group (n=26), computer-assisted training group (n=33) and telerehabilitation training group (n=22). All the patients accepted medicine to facilitate the recovery of memory. Besides, the computer-assisted training group and the telerehabilitation training group accepted memory-based training programs with cognitive rehabilitation system locally or on network respectively, for six weeks. They were evaluated with Wechsler Memory Scale, Rivermead Behavioural Memory Test-2nd Edition and Rey Auditory Verbal Learning Test before and after training. Results Both computer-assisted and telerehabilitation training groups improved in all the assessment after training (t>4.059, P<0.001). There was no significant difference between them (P>0.05). There was no significant improvement in the control group after training (t<0.771, P>0.05). Conclusion Memory rehabilitation training can significantly improve memory abilities, similar with locally or telerehabilitation system.