CJRTP

Chinese Journal of Rehabilitation Theory and Practice >

2016 , Vol. 22 >Issue 11: 1281 - 1284

DOI: https://doi.org/10.3969/j.issn.1006-9771.2016.11.008

Role of Notch Signaling Pathway in Neurogenesis in Central Nervous System (review)

  • ZOU Li-liang ,
  • WANG Kui ,
  • MAN Xia-nan ,
  • CHEN Jian-er
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  • Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China

Online published: 2016-12-05

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Abstract

The Notch signaling pathway plays a pivotal role in the process of neurogenesis in central nervous system. It not only maintains the appropriate number and proportion of neurons and glial cells in the growth and development of embryo, but also regulates the injured neural stem/progenitor cells to differentiate into neurons/glial cells of the adult nervous system, promoting the repair of the nervous system.

Key words： Notch; signaling pathway; central nervous system; neurogenesis; neural stem cell; neural progenitor cell; review

Cite this article

ZOU Li-liang , WANG Kui , MAN Xia-nan , CHEN Jian-er . Role of Notch Signaling Pathway in Neurogenesis in Central Nervous System (review)[J]. Chinese Journal of Rehabilitation Theory and Practice, 2016 , 22(11) : 1281 -1284 . DOI: 10.3969/j.issn.1006-9771.2016.11.008

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