CJRTP

Chinese Journal of Rehabilitation Theory and Practice >

2017 , Vol. 23 >Issue 5: 497 - 500

DOI: https://doi.org/10.3969/j.issn.1006-9771.2017.05.001

Concept and Pathophysiology of Post-polio Syndrome (review)

  • ZHANG Ai-min ,
  • WANG Yu-ming ,
  • GONG Hui-ming ,
  • ZHANG Jun-yi ,
  • SUN Qing ,
  • ZHANG Ran ,
  • LI Jing
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  • 1. Research Institute of Rehabilitation Information, China Rehabilitation Research Center, Beijing 100068, China;
    2. Department of Spinal and Neural Functional Reconstruction, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    3. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    4. Dongsheng People's Hospital, Erdos, Inner Mongolia 017000, China

Received date: 2016-11-23

  Revised date: 2017-02-09

  Online published: 2017-05-24

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Abstract

Post-polio syndrome (PPS) is a syndrome after acute infection of poliovirus and sequelae of polio. The incidence of PPS is high, and more in old patients. The pathological features of PPS include chronic nerve damage affected muscles, result in fatigue, pain, breathing and sleep disorders, fall risk, and so on, which impair their health and quality of life. The hypotheses of pathogenesis of PPS include over load of motor neurons, and the continuous existence of the poliovirus, etc. PPS is a stable neuromuscular disease progressing slowly.

Key words： post-polio syndrome; pathophysiology; review

Cite this article

ZHANG Ai-min , WANG Yu-ming , GONG Hui-ming , ZHANG Jun-yi , SUN Qing , ZHANG Ran , LI Jing . Concept and Pathophysiology of Post-polio Syndrome (review)[J]. Chinese Journal of Rehabilitation Theory and Practice, 2017 , 23(5) : 497 -500 . DOI: 10.3969/j.issn.1006-9771.2017.05.001

References

[1] Oshinsky DM. 他们应当行走——美国往事之小儿麻痹症[M]. 阳曦,译. 北京:清华大学出版社, 2015.
[2] Boyer FC, Tiffreau V, Rapin A, et al. Post-polio syndrome: Pathophysiological hypotheses, diagnosis criteria, drug therapy [J]. Ann Phys Rehabil Med, 2010, 53(1): 34-41.
[3] Baj A, Colombo M, Headley JL, et al. Post-poliomyelitis syndrome as a possible viral disease [J]. Int J Infect Dis, 2015, 35(6): 107-116.
[4] 王波,李晓华,赵辉,等. 骨小梁金属髋臼杯在脊髓灰质炎后遗症患者非瘫痪侧全髋关节置换术中的应用[J]. 中华关节外科杂志(电子版), 2015, 9(6): 45-49.
[5] 王华. 脊髓灰质炎[J]. 中国实用儿科杂志, 2007, 22(7): 481-483.
[6] 周夏俊,陈升东,管阳太. 脊髓灰质炎后综合征样表现多发性肌炎1例[J]. 复旦学报(医学版), 2012, 39(5): 545-547.
[7] 王波,李立明. 国际公共卫生新进展[J]. 中华流行病学杂志, 2016, 37(1): 1-4.
[8] Pierini D, Stuifbergen AK. Psychological resilience and depressive symptoms in older adults diagnosed with post-polio syndrome [J]. Rehabil Nurs, 2010, 35(4): 167-175.
[9] 相波,李喜梅,王晓青. 小细胞肺癌并副癌综合征误诊为脊髓灰质炎后综合征分析(附1例报告)[J]. 青岛大学医学院学报, 2012, 48(2): 175-176.
[10] Trojan DA, Cashman NR. Post-poliomyelitis syndrome [J]. Muscle Nerve, 2005, 31(1): 6-19.
[11] Gonzalez H, Olsson T, Borq K. Management of postpolio sydrome [J]. Lancet Neurol, 2010, 9(6): 634-642.
[12] Bridgens R, Sturman S, Davidson C, et al. Post-polio syndrome–polios legacy [J]. Clin Med, 2010, 10(3): 213-214.
[13] 李海燕,杨清成,齐尚书,等. 脊髓灰质炎后综合征1例临床病理特点及文献复习[J]. 临床荟萃, 2010, 25(6): 533-535.
[14] 侯世芳,李凯,刘银红. 脊髓灰质炎后综合征[J]. 中国神经免疫学和神经病学杂志, 2011, 18(4): 273-275.
[15] 李妍,黄天龙,张朝东,等. 脊髓灰质炎后综合征2例[J]. 中国临床神经科学, 2012, 20(6): 680-681.
[16] 何超明,马越,汤颖. 脊髓灰质炎后综合征1例报道[J]. 国际神经病学神经外科学杂志, 2013, 40(1): 35-36.
[17] 丁云龙,赵艳霞,唐冰,等. 脊髓灰质炎后综合征一例[J]. 脑与神经疾病杂志, 2013, 21(1): 62-63.
[18] 孙雪纯,赵哲. 脊髓灰质炎后综合征临床及电生理研究[J]. 国际神经病学神经外科学杂志, 2015, 42(6): 501-504.
[19] Laffont I, Julia M, Tiffreau V, et al. Aging and sequelae of poliomyelitis [J]. Ann Phys Rehabil Med, 2010, 53(1): 24-33.
[20] Hachisuka A, Komori T, Abe T, et al. Repeater F-waves are signs of motor unit pathology in polio survivors [J]. Muscle Nerve, 2015, 51(5): 680-685.
[21] 王必佳,陈康宁,李勇湧,等. 肌电图在鉴别诊断运动神经元病、腓骨肌萎缩症和脊髓灰质炎后综合征中的价值[J]. 第三军医大学学报, 2012, 34(21): 2218-2219.
[22] Tiffreau V, Rapin A, Serafi R, et al. Post-polio syndrome and rehabilitation [J]. Ann Phys Rehabil Med, 2010, 53(1): 42-50.
[23] LaRocco SA. Post-polio syndrome: unraveling the mystery [J]. Nursing, 2011, 41(2): 26-29.
[24] Maeda K, Joko M. Segmental muscular atrophy in a patient with post polio syndrome [J]. Intern Med, 2007, 46(2): 75-76.
[25] Lira CA, Minozzo FC, Sousa BS, et al. Lung function in post-poliomyelitis syndrome: a cross-sectional study [J]. J Bras Pneumol, 2013, 39(4): 455-460.
[26] Melin E, Lindroos E, Lundberg IE, et al. Elevated expression of prostaglandin E2 synthetic pathway in skeletal muscle of prior polio patients [J]. J Rehabil Med, 2014, 46(1): 67-72.
[27] Oki R, Uchino A, Izumi Y, et al. An autopsy case of progressive generalized muscle atrophy over 14 years due to post-polio syndrome [J]. Rinsho Shinkeigaku, 2016, 56(1): 12-16.
[28] Melin E, Kahan T, Borg K. Elevated blood lipids are uncommon in patients with post-polio syndrome–a cross sectional study [J]. BMC Neurol, 2015, 29(2): 67.
[29] Stolwijk-Swüste JM, Beelen A, Lankhorst G, et al. Impact of age and co-morbidity on the functioning of patients with sequelae of poliomyelitis: a cross-sectional study [J]. J Rehabil Med, 2007, 39(1): 56-62.
[30] McNalley TE, Yorkston KM, Jensen MP, et al. Review of secondary health conditions in post polio syndrome: prevalence and effects of aging [J]. Am J Phys Med Rehabil, 2015, 94(2): 139-145.
[31] Bouza C, Munoz A, Amate JM. Postpolio syndrome: a challenge to the health-care system [J]. Health Policy, 2005, 71(1): 97-106.
[32] Bertolasi L, Acler M, Dall'Ora E, et al. Risk factors for post-polio syndrome among an Italian population: a case-control study [J]. Neurol Sci, 2012, 33(6): 1271-1275.
[33] Davidson AC, Auyeung V, Luff R, et al. Prolonged benefit in post-polio syndrome from comprehensive rehabilitation: a pilot study [J]. Disabil Rehabil, 2009, 31(4): 309-317.
[34] Bickerstaffe A, Beelen A, Nollet F. Change in physical mobility over 10 years in post-polio syndrome [J]. Neuromuscul Disord, 2015, 25(3): 225-230.
[35] Bickerstaffe A, Beelen A, Nollet F. Circumstances and consequences of falls in polio survivors [J]. J Rehabil Med, 2010, 42(10): 908-915.
[36] Willén C, Thorén-Jönsson AL, Grimby G, et al. Disability in a 4-year follow-up study of people with post-polio syndrome [J]. J Rehabil Med, 2007, 39(2): 175-180.
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