[1] Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics–2013 update: a report from the American Heart Association [J]. Circulation, 2013, 127(1): e6-e245.
[2] 王琴,张春银. 小动物PET在缺血性脑血管病中的应用进展[J]. 中国医学影像技术, 2014, 30(7): 1117-1120.
[3] 李冬梅,万春丽,李继承. 小动物活体成像技术研究进展[J]. 中国生物医学工程学报, 2009, 28(6): 916-921.
[4] 胡华,苏亮,施慎逊,等. 小动物PET技术在精神疾病模型研究中的应用[J]. 上海精神医学, 2010, 22(2): 115-118.
[5] Takasawa M, Beech JS, Fryer TD, et al. Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: a microPET study [J]. Exp Neurol, 2011, 229(2): 251-258.
[6] Balsara RD, Chapman SE, Sander IM, et al. Non-invasive imaging and analysis of cerebral ischemia in living rats using positron emission tomography with 18 F-FDG [J]. J Vis Exp, 2014(94): 1-10.
[7] Koo V, Hamilton PW, Williamson K. Non-invasive in vivo imaging in small animal research [J]. Cell Oncol, 2006, 28(4): 127-139.
[8] 刘卓然. 微PET在临床前研究中的应用[J]. 临床医药实践, 2012, 21(2): 120-123.
[9] Bruehl C, Witte OW. Cellular activity underlying altered brain metabolism during focal epileptic activity [J]. Ann Neurol, 1995, 38(3): 414-420.
[10] Chugani HT, Hovda DA, Villablanca JR, et al. Metabolic maturation of the brain: a study of local cerebral glucose utilization in the developing cat [J]. J Cereb Blood Flow Metab, 1991, 11(1): 35-47.
[11] 王中娟,邓钢,黄洪波,等. 7.0 T MRI及Micro-PET无创检测小鼠动脉粥样硬化[J]. 中国医学影像技术, 2010, 26(2): 209-212.
[12] Davies JR, Izquierdo-Garcia D, Rudd JH, et al. FDG-PET can distinguish inflamed from non-inflamed plaque in an animal model of atherosclerosis [J]. Int J Cardiovasc Imaging, 2010, 26(1): 41-48.
[13] 王晓云,朱文斌,陈雪梅,等. 兔大脑中动脉局灶性脑缺血模型制作和正电子发射断层显像观察[J]. 中国脑血管病杂志, 2007, 4(1): 32-36.
[14] Lansberg MG, Albers GW, Beaulieu C, et al. Comparison of diffusion-weighted MRI and CT in acute stroke [J]. Neurology, 2000, 54(8): 1557-1561.
[15] Liebelt B, Papapetrou P, Ali A, et al. Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2 [J]. Neuroscience, 2010, 166(4): 1091-1100.
[16] Zwagerman N, Sprague S, Davis MD, et al. Pre-ischemic exercise preserves cerebral blood flow during reperfusion in stroke [J]. Neurol Res, 2010, 32(5): 523-529.
[17] 梁胜,黄秋,李彪. Micro PET/CT用于急性缺血性中风早期功能性血管再生的研究[C]. 西安:中华医学会第九次全国核医学学术会议, 2011.
[18] Baron JC. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications [J]. Cerebrovasc Dis, 2001, 11(Suppl 1): 2-8.
[19] Bernaudin M, Nedelec AS, Divoux D, et al. Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain [J]. J Cereb Blood Flow Metab, 2002, 22(4): 393-403.
[20] Jung JE, Kim GS, Chen H, et al. Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection [J]. Mol Neurobiol, 2010, 41(2-3): 172-179.
[21] Saita K, Chen M, Spratt NJ, et al. Imaging the ischemic penumbra with 18 F-fluoromisonidazole in a rat model of ischemic stroke [J]. Stroke, 2004, 35(4): 975-980.
[22] Takasawa M, Beech JS, Fryer TD, et al. Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18 F-fluoromisonidazole and positron emission tomography: a pilot study [J]. J Cereb Blood Flow Metab, 2007, 27(4): 679-689.
[23] 张运周,朱克,尹岭, 等. 猫大脑中动脉闭塞后缺血脑组织早期葡萄糖代谢的研究[J]. 中华神经科杂志, 2002, 35(1): 25-28.
[24] Sobrado M, Delgado M, Fernandez-Valle E, et al. Longitudinal studies of ischemic penumbra by using 18 F-FDG PET and MRI techniques in permanent and transient focal cerebral ischemia in rats [J]. Neuroimage, 2011, 57(1): 45-54.
[25] Gao F, Wang S, Guo Y, et al. Protective effects of repetitive transcranial magnetic stimulation in a rat model of transient cerebral ischemia: a microPET study [J]. Eur J Nucl Med Mol Imaging, 2010, 37(5): 954-961.
[26] Badr AE, Yin W, Mychaskiw G, et al. Dual effect of HBO on cerebral infarction in MCAO rats [J]. Am J Physiol Regul Integr Comp Physiol, 2001, 280(3): R766-R770.
[27] Lou M, Eschenfelder CC, Herdegen T, et al. Therapeutic window for use of hyperbaric oxygenation in focal transient ischemia in rats [J]. Stroke, 2004, 35(2): 578-583.
[28] 冯娟娟. 即时高压氧对局灶性脑缺血再灌注大鼠脑梗死体积的影响[D]. 沈阳:中国医科大学, 2009.
[29] Lou M, Zhang H, Wang J, et al. Hyperbaric oxygen treatment attenuated the decrease in regional glucose metabolism of rats subjected to focal cerebral ischemia: a high resolution positron emission tomography study [J]. Neuroscience, 2007, 146(2): 555-561.
[30] 田浩梅,张泓,张娟,等. 针灸对缺血性脑卒中相关保护作用机制的研究概况[J]. 湖南中医药大学学报, 2012, 32(7): 75-78.
[31] Liu H, Shen X, Tang H, et al. Using microPET imaging in quantitative verification of the acupuncture effect in ischemia stroke treatment [J]. Sci Rep, 2013, 3: 1070.
[32] 黄伟. 超早期针刺对急性脑缺血大鼠能量代谢的影响及其机制研究[D]. 武汉:湖北中医药大学, 2010.
[33] 江晓峰,张通. 康复训练对局灶性脑缺血大鼠葡萄糖代谢的影响——MicroPET纵向研究[C]. 北京:第五届北京国际康复论坛, 2010.
[34] Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors [J]. Cell, 2006, 126(4): 663-676.
[35] Wang J, Chao F, Han F, et al. PET demonstrates functional recovery after transplantation of induced pluripotent stem cells in a rat model of cerebral ischemic injury [J]. J Nucl Med, 2013, 54(5): 785-792.
[36] Du S, Guan J, Mao G, et al. Intra-arterial delivery of human bone marrow mesenchymal stem cells is a safe and effective way to treat cerebral ischemia in rats [J]. Cell Transplant, 2014, 23(Suppl 1): S73-S82.
[37] 郑晓娟. 野黄芩苷抗缺血性脑损伤作用及机制研究[D]. 上海:上海医药工业研究院, 2006.
[38] Wan H, Zhu H, Tian M, et al. Protective effect of Chuanxiongzine-puerarin in a rat model of transient middle cerebral artery occlusion-induced focal cerebral ischemia [J]. Nucl Med Commun, 2008, 29(12): 1113-1122.
[39] Yang J, Li J, Lu J, et al. Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia [J]. J Ethnopharmacol, 2012, 140(1): 64-72.
[40] 华续赟. 健神经移位治疗中枢损伤后上肢偏瘫的应用研究[D]. 上海:复旦大学, 2012.
[41] 刘杰,金玉萍,白玉海,等. PET-CT与MRI观察短暂性脑缺血发作后脑缺血改变的对比研究[J]. 黑龙江医学, 2010, 34(1): 25-26.
[42] 张晶,蒋亚超,曹卫,等. 小动物PET在神经科学研究中的应用[J]. 科学通报, 2011, 56(23): 1871-1876.
