Effect of Botulinum Toxin Type A on Spastic Cerebral Palsy: Two Years Follow-up

  • LIU Jian-jun ,
  • QI Jing ,
  • ZHANG Yan ,
  • ZENG Fan-yong ,
  • LI Nan-ling ,
  • XI Bing-yu ,
  • WU Wei-hong
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  • 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    2. Beijing Bo'ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China

Received date: 2016-10-31

  Online published: 2017-08-07

Abstract

ObjectiveTo investigate the long-term effect of Botulinum toxin type A (BTX-A) block on spasticity in cerebral palsy. MethodsFrom June, 2005 to December, 2013, 51 children with spastic cerebral palsy accepted routine rehabilitation with (trial group, n=24) or without (control group, n=27) BTX-A block. They were assessed with modified Ashworth Scale (MAS), Physician Rating Scale (PRS) and Gross Motor Function Measure (GMFM) before treatment, and with PRS and GMFM two years after treatment. ResultsThere was no significant difference between two groups in ages, body mass, and scores of MAS, PRS and GMFM before treatment (t<1.207, χ2=0.076, P>0.05). The scores of PRS and GMFM improved in both groups two years after treatment (t>2.217, P<0.05), and improved more in the trial group than in the control group (t>2.095, P<0.05). ConclusionThe long-term effect of BTX-A block is positive. The rehabilitation training after block can promote their motor function recovery.

Cite this article

LIU Jian-jun , QI Jing , ZHANG Yan , ZENG Fan-yong , LI Nan-ling , XI Bing-yu , WU Wei-hong . Effect of Botulinum Toxin Type A on Spastic Cerebral Palsy: Two Years Follow-up[J]. Chinese Journal of Rehabilitation Theory and Practice, 2017 , 23(7) : 816 -819 . DOI: 10.3969/j.issn.1006-9771.2017.07.017

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