CONTENTS

Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation at Uninjured Side on Memory and Quality of Life in Patients with Traumatic Brain Injury

  • WANG Dan ,
  • MAI Rong-kang ,
  • WANG Min ,
  • TAN Ting-ting ,
  • ZHU Fen ,
  • CHEN Shang-jie ,
  • HUANG Ju-ke
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  • Department of Rehabilitation, the Affiliated Shenzhen Bao'an Hospital of Southern Medical University, Shenzhen, Guangdong 518101, China

Received date: 2017-01-22

  Revised date: 2017-06-09

  Online published: 2017-11-03

Abstract

Objective To observe the effect of low frequency repetitive transcranial magnetic stimulation at uninjured side on memory and quality of life in patients with traumatic brain injury.Methods From September, 2013 to June, 2015, 60 cases of memory impairment after traumatic brain injury were randomly divided into control group (n=30) and observation group (n=30). The control group was given neurosurgical conventional treatment; the observation group was given low frequency repetitive transcranial magnetic stimulation in addition, for four weeks. The scores of Rivermead Behavior Memory Test (RBMT) and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) were observed before and after treatment in both groups.Results After treatment, there was no significant difference in the RBMT score in the control group (t=1.233, P=0.223); the RBMT score increased in the observation group (t=2.186, P=0.033); and there was no significant difference between two groups (t=1.133, P=0.262). After treatment, the WHOQOL-BREF score increased in physical health in the control group (t=5.606, P<0.001), while it increased in the physical, psychological health, and environment in the observation group (t>2.879, P<0.01), which were higher in the observation group than in the control group (t>2.095, P<0.05). There was no significant difference in the social relationship between two groups (t=0.508, P=0.614).Conclusion Low frequency repetitive transcranial magnetic stimulation at uninjured side could improve the memory ability and quality of life for patients with traumatic brain injury.

Cite this article

WANG Dan , MAI Rong-kang , WANG Min , TAN Ting-ting , ZHU Fen , CHEN Shang-jie , HUANG Ju-ke . Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation at Uninjured Side on Memory and Quality of Life in Patients with Traumatic Brain Injury[J]. Chinese Journal of Rehabilitation Theory and Practice, 2017 , 23(10) : 1180 -1184 . DOI: 10.3969/j.issn.1006-9771.2017.10.012

References

[1] 励建安. 脑外伤康复的现状与未来发展趋势[J]. 中国康复医学杂志, 2011, 26(12): 1095-1097.
[2] Lefaucheur JP, André-Obadia N, Antal A, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) [J]. Clin Neurophysiol, 2014, 125(11): 2150-2206.
[3] Mioni G, Rendell PG, Terrett G, et al. Prospective memory performance in traumatic brain injury patients: a study of implementation intentions [J]. J Int Neuropsychol Soc, 2015, 21(4): 305-313.
[4] 左克俭,韩国玲. 影响脑外伤后生活质量的相关因素研究[J]. 神经疾病与精神卫生, 2007, 7(4): 288-290.
[5] 郭华珍,恽晓平. Rivermead行为记忆测验第2版介绍[J]. 中国康复理论与实践, 2007, 13(10): 909-910.
[6] 郝元涛,方积乾. 世界卫生组织生存质量测定量表中文版介绍及其使用说明[J]. 现代康复, 2000, 4(8): 1127-1129
[7] Nadeau SE, Bowers D, Jones TL, et al. Cognitive effects of treatment of depression with repetitive transcranial magnetic stimulation [J]. Cogn Behav Neurol, 2014, 27(2): 77-87.
[8] Wobrock T, Guse B, Cordes J, et al. Left prefrontal high-frequency repetitive transcranial magnetic stimulation for the treatment of schizophrenia with predominant negative symptoms: a sham-controlled, randomized multicenter trial [J]. Biol Psychiatry, 2015, 77(11): 979-988.
[9] Noohi S, Amirsalari S. History, studies and specific uses of repetitive transcranial magnetic stimulation (rTMS) in treating epilepsy [J]. Iran J Child Neurol, 2016, 10(1): 1-8.
[10] Wagle Shukla A, Shuster JJ, Chung JW, et al. Repetitive transcranial magnetic stimulation (rTMS) therapy in Parkinson disease: a meta-analysis [J]. PM&R, 2016, 8(4): 356-366.
[11] 黄居科,麦荣康,陈尚杰. 低频重复经颅磁刺激对脑外伤患者认知功能和功能独立的影响[J]. 中华神经医学杂志, 2009, 8(8): 854-856.
[12] Herrold AA, Kletzel SL, Harton BC, et al. Transcranial magnetic stimulation: potential treatment for co-occurring alcohol, traumatic brain injury and posttraumatic stress disorders [J]. Neural Regen Res, 2014, 9(19): 1712-1730.
[13] Kreuzer PM, Landgrebe M, Frank E, et al. Repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus after traumatic brain injury: a case study [J]. J Head Trauma Rehabil, 2013, 28(5): 386-389.
[14] Miniussi C, Cappa SF, Cohen LG, et al. Efficacy of repetitive transcranial magnetic stimulation/transcranial direct current stimulation in cognitive neurorehabilitation [J]. Brain Stimul, 2008, 1(4): 326-336.
[15] 芦海涛,孙莉,郭华珍,等. 低频重复经颅磁刺激对脑卒中后记忆及认知功能的影响[J]. 中国康复理论与实践, 2015, 21(9): 1074-1077.
[16] 赵秀秀,韩肖华,张靖慧,等. 高频重复经颅磁刺激对大鼠脑梗死后学习记忆功能及pCREB、bcl-2、bax表达的影响[J]. 中国康复医学杂志, 2012, 27(12): 1087-1092.
[17] Gaudeau-Bosma C, Moulier V, Allard AC, et al. Effect of two weeks of rTMS on brain activity in healthy subjects during an n-back task: a randomized double blind study [J]. Brain Stimul, 2013, 6(4): 569-575.
[18] 闫丽丽,陶华英. 重复经颅磁刺激对轻度认知功能障碍患者记忆功能改善作用的研究[J]. 中华老年心脑血管病杂志, 2011, 13(5): 438-441.
[19] 王婷婷,莫雷,舒斯云. 记忆编码与提取过程的脑机制——功能性核磁共振研究[J]. 生理学报, 2009, 61(5): 395-403.
[20] Klomjai W, Katz R, Lackmy-Vallée A. Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) [J]. Ann Phys Rehabil Med, 2015, 58(4): 208-213.
[21] Blesneag AV, Slăvoacă DF, Popa L, et al. Low-frequency rTMS in patients with subacute ischemic stroke: clinical evaluation of short and long-term outcomes and neurophysiological assessment of cortical excitability [J]. J Med Life, 2015, 8(3): 378-387.
[22] Takekawa T, Kakuda W, Uchiyama M, et al. Brain perfusion and upper limb motor function: a pilot study on the correlation between evolution of asymmetry in cerebral blood flow and improvement in Fugl-Meyer Assessment score after rTMS in chronic post-stroke patients [J]. J Neuroradiol, 2014, 41(3): 177-183.
[23] 户东梅,程肖蕊,周文霞,等. 重复经颅磁刺激对脑卒中后认知功能障碍治疗的研究进展[J]. 生理科学进展, 2012, 43(6): 411-416.
[24] 何成松,余茜,杨大鉴,等. 低频重复经颅磁刺激对脑损伤后抑郁症患者的干预效应[J]. 中国临床康复, 2004, 8(28): 6044-6045.
[25] 张婧,赵文博,俞志鹏. 重复经颅磁刺激治疗卒中后抑郁随机对照试验Meta分析[J]. 中国实用神经疾杂志, 2015, 18(11): 30-33.
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