Objective To explore the effects of individual aerobic and resistance training on the blood glucose, cardiopulmonary fitness, body composition and quality of life for patients with type 2 diabetes mellitus (T2DM). Methods From September, 2016 to December, 2017, 120 patients with T2DM were randomly assigned to control group (n = 40), aerobic training group (n = 40) and combined training group (n = 40). All the patients accepted routine medication, health education and diet guide, while the aerobic training group accepted target heart rate aerobic exercises according to the cardiopulmonary exercise test and the combined training group accepted resistance training based on the aerobic training group. They were measured the blood glucose, cardiopulmonary fitness, body composition and quality of life before and after three months of treatment. Results The fasting blood glucose (FBG), hemoglobin A1c (HbA1C), insulin resistance index (HOMA-IR), peak exercise load, anaerobic threshold, peak oxygen consumption, metabolic equivalent, oxygen pulse, carbon dioxide ventilation equivalent slope, fat mass (FM), lean body mass (LBM) and the scores of quality of life improved after treatment in both training groups (t > 2.422, P < 0.05), and FBG, HbA1C, HOMA-IR, peak exercise load, LBM and the scores of quality of life improved more in the combined training group than in the aerobic training group (P < 0.05). Conclusion Combining with resistance training based on aerobic training can further improve blood glucose, body composition and quality of life in patients with T2DM, but no more effect on the cardiopulmonary fitness.
[1] 晁敏,梁丰,王尊,等. 不同强度有氧运动对2型糖尿病患者生理指标的影响[J]. 中国康复医学杂志, 2015, 30(9): 883-887.
[2] International Diabetes Federation. IDF Diabetes Atlas: seventh edition [EB/OL]. (2017-03-16). http://www.diabetesatlas.org/.
[3] 常凤,杜可新,李国平. 不同运动方案对中年2型糖尿病患者健康体适能促进效果的临床疗效观察[J]. 中国康复医学杂志, 2018, 33(5): 559-564,568.
[4] American Diabetes Association.Standards of Medical Care in Diabetes-2010[J]. Diabetes Care, 2010, 33(Suppl 1): S11-S61.
[5] 美国运动医学学会. ACSM运动测试与运动处方指南[M]. 北京:北京体育大学出版社, 2014: 54-56.
[6] 中华医学会糖尿病学分会. 中国糖尿病运动指南[EB/OL]. (2012-12-20). http://guide.medlive.cn/guideline/4659.
[7] 李源源,方奋,贾占昀,等. 不同强度有氧运动对2型糖尿病患者血糖及心肺耐力的影响[J]. 中华物理医学与康复杂志, 2017, 39(8): 617-619.
[8] 杜可新,匡洪宇. 运动促进2型糖尿病患者骨骼肌葡萄糖摄取机制研究进展[J]. 中华实用诊断与治疗杂志, 2016, 30(10): 943-945.
[9] 陈炳霖,张宏卫,郭佳宝,等. 糖尿病前期运动疗法研究现状[J]. 中国运动医学杂志, 2017, 36(11): 1012-1016.
[10] Vinetti G, Mozzini C, Desenzani P, et al.Supervised exercise training reduces oxidative stress and cardiometabolic risk in adults with type 2 diabetes: a randomized controlled trial[J]. Sci Rep, 2015,5(7): 9238.
[11] AminiLari Z, Fararouei M, Amanat S, et al. The effect of 12 weeks aerobic, resistance, and combined exercises on omentin-1 levels and insulin resistance among type 2 diabetic middle-aged women[J]. Diabetes Metab J, 2017, 41(3): 205-212.
[12] 李小玲,陈贤,李凌云,等. 不同运动方式广场舞对老年2型糖尿病患者血糖及心肺功能的影响[J]. 齐鲁护理杂志, 2015, 21(23): 14-16.
[13] Byrkjeland R, Stensæth KH, Anderssen S, et al.Effects of exercise training on carotid intima-media thickness in patients with type 2 diabetes and coronary artery disease. Influence of carotid plaques[J]. Cardiovasc Diabetol, 2016, 15:13.
[14] Alvarez C, Ramírez-Campillo R, Ramírez-Vélez R.Effects of 6-weeks high-intensity interval training in schoolchildren with insulin resistance: influence of biological maturation on metabolic, body composition, cardiovascular and performance non-responses[J]. Front Physiol, 2017, 29(8): 444.
[15] 汪亚群,楼青青,嵇加佳,等. 抗阻运动对糖尿病前期患者糖脂代谢的影响[J]. 中华物理医学与康复杂志, 2015, 37(4): 294-297.
[16] 孙兴国. 生命整体调控新理论体系与心肺运动试验[J]. 医学与哲学, 2013, 34(5): 22-27.
[17] 汪宇鹏,姚思华,刘丹,等. 老年冠心病患者骨骼肌质量比重与心肺耐力的相关性[J]. 中华医学杂志, 2018, 98(11): 831-836.
[18] Green S, Egaña M, Baldi JC, et al.Cardiovascular control during exercise in type 2 diabetes mellitus[J]. J Diabetes Res, 2015, 2015: 654204.
[19] Lin J, Gao M, Chen W, et al.Exercise training on chronotropic response and exercise capacity in patients with type 2 diabetes mellitus[J]. Exp Ther Med, 2017, 13(3): 899-904.
[20] Wagner H, Fischer H, Degerblad M, et al.Improvement of insulin sensitivity in response to exercise training in type 2 diabetes mellitus is associated with vascular endothelial growth factor A expression[J]. Diab Vasc Dis Res, 2016, 13(5): 361-366.
[21] Gordon JW, Dolinsky VW, Mughal W, et al.Targeting skeletal muscle mitochondria to prevent type 2 diabetes in youth[J]. Biochem Cell Biol, 2015, 93(5): 452-465.
[22] Sénéchal M, Johannsen NM, Swift DL, et al.Association between changes in muscle quality with exercise training and changes in cardiorespiratory fitness measures in individuals with type 2 diabetes mellitus: results from the HART-D Study[J]. PLoS One, 2015, 10(8): e0135057.
[23] Liu Y, Liu SX, Cai Y, et al.Effects of combined aerobic and resistance training on the glycolipid metabolism and inflammation levels in type 2 diabetes mellitus[J]. J Phys Ther Sci, 2015, 27(7): 2365-2371.
[24] Gaudet JL, Mekary S, BéLanger M, et al. Effects of an aerobic exercise program on driving performance in adults with cardiovascular disease[J]. Int J Rehabil Res, 2016, 39(2): l17-122.
[25] 程晶,陈伟,钟卫权. 等热量不同运动方式对2型糖尿病患者血管内皮及心肺功能的影响[J]. 中国康复医学杂志, 2016, 31(9): 1018-1020.
[26] Bacchi E, Negri C, Zanolin ME, et al.Metabolic effects of aerobic training and resistance training in type 2 diabetes subjects: a randomized controlled trial[J]. Diabetes Care, 2012, 35(4): 676-682.
[27] Jennings AE, Alberga A, Sigal RJ, et al.The effect of exercise training on resting metabolic rate in type 2 diabetes mellitus[J]. Med Sci Sports Exerc, 2009, 4l(8): 1558-1565.
[28] Argani N, Sharifi G.Comparison of the effect of different intensity exercise on a bicycle ergometer on postprandial lipidemia in type II diabetic patients[J]. ARYA Atheroscler, 2014,10(3):147-153.
[29] Socha M, Fraczak P, Jonak W, et al.Effect of resistance training with elements of stretching on body composition and quality of life in postmenopausal women[J]. Prz Menopauzalny, 2016, 15(1): 26-31.
