Advance in Exercise and Related Mechanisms for Parkinson's Disease (review)

  • LI Ya-hui ,
  • LI Xiao-hong
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  • 1. Dalian Medical University, Dalian, Liaoning 116001, China;
    2. Dalian Friendship Hospital, Dalian Medical University, Dalian, Liaoning 116001, China

Received date: 2018-06-04

  Revised date: 2018-09-26

  Online published: 2019-02-18

Abstract

Parkinson's disease is a common degenerative disease of central nervous system. Exercise for Parkinson's disease includes Taiji Quan, treadmill, dance and balance training, etc. Taiji Quan exercise is mainly for balance function, and treadmill training for gait obstacles. Dance can improve not only balance and gait, but also cognition and emotion. The possible molecular mechanism may involve to adjust the content of dopaminergic neurons in the nigrostatin, increase the content of non-dopaminergic transmitters, increase brain-derived neurotrophic factors, promote the plasticity of nerve cells, reduce oxidative stress, enhance mitochondrial activity, and activate the immune system, etc., to slow the degeneration of dopaminergic neurons and improve the symptoms of Parkinson's disease.

Cite this article

LI Ya-hui , LI Xiao-hong . Advance in Exercise and Related Mechanisms for Parkinson's Disease (review)[J]. Chinese Journal of Rehabilitation Theory and Practice, 2019 , 25(1) : 51 -54 . DOI: 10.3969/j.issn.1006-9771.2018.00.010

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