Advance in Repetitive Transcranial Magnetic Stimulation for Alzheimer's Disease (review)

  • HUANG Na-yan ,
  • SONG Lu-ping ,
  • TONG Zhi-qian ,
  • WEI Cui-bai ,
  • Lü Ji-hui
Expand
  • 1.Center for Cognitive Disorders, Beijing Geriatric Hospital, Beijing 100095, China
    2.Alzheimer’s Disease Center, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China
    3.Department of Neurology, Beijing Bo’ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
    4.Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received date: 2018-05-01

  Revised date: 2018-06-22

  Online published: 2019-04-02

Supported by

Capital Characteristic Clinic Project (No. Z151100004015023) and Beijing Municipal Administration of Hospitals Special Funding for Clinical Medicine Development (No. ZYLX201834)

Abstract

Repetitive transcranial magnetic stimulation (rTMS), a noninvasive and painless brain stimulation technique, can improve cognition and alleviate behavioral and psychological symptoms in patients with Alzheimer's disease through several mechanisms associated with neuronal plasticity, brain network, neurotransmitter, neurotrophic factors, and so on.

Cite this article

HUANG Na-yan , SONG Lu-ping , TONG Zhi-qian , WEI Cui-bai , Lü Ji-hui . Advance in Repetitive Transcranial Magnetic Stimulation for Alzheimer's Disease (review)[J]. Chinese Journal of Rehabilitation Theory and Practice, 2019 , 25(3) : 261 -266 . DOI: 10.3969/j.issn.1006-9771.2019.03.003

References

1 PfaffD W. Neuroscience in the 21st Century: from Basic to Clinical [M]. New York: Springer, 2013: 1255-1288, 2953-2969.
2 AssociationAlzheimer's. 2016 Alzheimer's disease facts and figures [J]. Alzheimers Dement, 2016, 12(4): 459-509.
3 NardoneR, BergmannJ, ChristovaM, et al. Effect of transcranial brain stimulation for the treatment of Alzheimer disease: a review [J]. Int J Alzheimers Dis, 2012, 2012: 687909.
4 SiebnerH R, HartwigsenG, KassubaT, et al. How does transcranial magnetic stimulation modify neuronal activity in the brain? Implications for studies of cognition [J]. Cortex, 2009, 45(9): 1035-1042.
5 LefaucheurJ P, Andre-ObadiaN, AntalA, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) [J]. Clin Neurophysiol, 2014, 125(11): 2150-2206.
6 CotelliM, ManentiR, CappaS F, et al. Effect of transcranial magnetic stimulation on action naming in patients with Alzheimer disease [J]. Arch Neurol, 2006, 63(11): 1602-1604.
7 CotelliM, ManentiR, CappaS F, et al. Transcranial magnetic stimulation improves naming in Alzheimer disease patients at different stages of cognitive decline [J]. Eur J Neurol, 2008, 15(12): 1286-1292.
8 CotelliM, CalabriaM, ManentiR, et al. Improved language performance in Alzheimer disease following brain stimulation [J]. J Neurol Neurosurg Psychiatry, 2011, 82(7): 794-797.
9 DeviG, VossH U, LevineD, et al. Open-label, short-term, repetitive transcranial magnetic stimulation in patients with Alzheimer's disease with functional imaging correlates and literature review [J]. Am J Alzheimers Dis Other Demen, 2014, 29(3): 248-255.
10 AhmedM A, DarwishE S, KhedrE M, et al. Effects of low versus high frequencies of repetitive transcranial magnetic stimulation on cognitive function and cortical excitability in Alzheimer's dementia [J]. J Neurol, 2012, 259(1): 83-92.
11 吴越,徐文炜,刘晓伟,等. 不同频率重复经颅磁刺激对阿尔茨海默病患者认知功能的影响[J]. 实用医学杂志, 2015, 31(10): 1624-1627.
12 EliasovaI, AnderkovaL, MarecekR, et al. Non-invasive brain stimulation of the right inferior frontal gyrus may improve attention in early Alzheimer's disease: a pilot study [J]. J Neurol Sci, 2014, 346(1-2): 318-322.
13 李如玉,赵希武,杨海波,等. 重复经颅磁刺激治疗老年性痴呆的效果及安全性[J]. 四川精神卫生, 2017, 30(2): 140-143.
14 SitzerD I, TwamleyE W, JesteD V. Cognitive training in Alzheimer's disease: a meta-analysis of the literature [J]. Acta Psychiatr Scand, 2006, 114(2): 75-90.
15 徐英,沈珍华,苏巍,等. 综合康复治疗对早中期阿尔茨海默病患者认知功能的影响[J]. 老年医学与保健, 2014, 20(3): 173-175.
16 BentwichJ, DobronevskyE, AichenbaumS, et al. Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study [J]. J Neural Transm (Vienna), 2011, 118(3): 463-471.
17 RabeyJ M, DobronevskyE, AichenbaumS, et al. Repetitive transcranial magnetic stimulation combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: a randomized, double-blind study [J]. J Neural Transm (Vienna), 2013, 120(5): 813-819.
18 RabeyJ M, DobronevskyE. Repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: clinical experience [J]. J Neural Transm (Vienna), 2016, 123(12): 1449-1455.
19 LeeJ, ChoiB H, OhE, et al. Treatment of Alzheimer's disease with repetitive transcranial magnetic stimulation combined with cognitive training: a prospective, randomized, double-blind, placebo-controlled study [J]. J Clin Neurol, 2016, 12(1): 57-64.
20 NguyenJ P, SuarezA, KemounG, et al. Repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease [J]. Neurophysiol Clin, 2017, 47(1): 47-53.
21 ZhaoJ, LiZ, CongY, et al. Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer's disease patients [J]. Oncotarget, 2017, 8(20): 33864-33871.
22 吴越,顾君,冷文娟,等. 应用重复经颅磁刺激治疗阿尔茨海默病患者精神行为症状的临床研究[J]. 中国康复医学杂志, 2011, 26(7): 672-673.
23 WuY, XuW, LiuX, et al. Adjunctive treatment with high frequency repetitive transcranial magnetic stimulation for the behavioral and psychological symptoms of patients with Alzheimer's disease: a randomized, double-blind, sham-controlled study [J]. Shanghai Arch Psychiatry, 2015, 27(5): 280-288.
24 吴越,徐文炜,刘晓伟,等. 重复经颅磁刺激对阿尔茨海默病患者精神行为症状及认知功能的影响[J]. 中华物理医学与康复杂志, 2017, 39(2): 131-135.
25 刘新,侯前梅,赵晓琼,等. 10 Hz重复经颅磁刺激对轻中度阿尔茨海默病患者的精神行为症状及注意执行的疗效观察[J]. 川北医学院学报, 2017, 32(3): 376-379.
26 陈燕. 神经元的突触可塑性与学习和记忆[J]. 生物化学与生物物理进展, 2008, 35(6): 610-619.
27 PilatoF, ProficeP, RanieriF, et al. Synaptic plasticity in neurodegenerative diseases evaluated and modulated by in vivo neurophysiological techniques [J]. Mol Neurobiol, 2012, 46(3): 563-571.
28 ChandG B, WuJ, HajjarI, et al. Interactions of the salience network and its subsystems with the default-mode and the central-executive networks in normal aging and mild cognitive impairment [J]. Brain Connect, 2017, 7(7): 401-412.
29 ZhouJ, GreiciusM D, GennatasE D, et al. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease [J]. Brain, 2010, 133(Pt 5): 1352-1367.
30 AgostaF, PievaniM, GeroldiC, et al. Resting state fMRI in Alzheimer's disease: beyond the default mode network [J]. Neurobiol Aging, 2012, 33(8): 1564-1578.
31 ConnorB, DragunowM. The role of neuronal growth factors in neurodegenerative disorders of the human brain [J]. Brain Res Brain Res Rev, 1998, 27(1): 1-39.
32 NilssonP, IwataN, MuramatsuS, et al. Gene therapy in Alzheimer's disease-potential for disease modification [J]. J Cell Mol Med, 2010, 14(4): 741-757.
33 TianL, GuoR, YueX, et al. Intranasal administration of nerve growth factor ameliorate beta-amyloid deposition after traumatic brain injury in rats [J]. Brain Res, 2012, 1440: 47-55.
34 CovaceuszachS, CapsoniS, UgoliniG, et al. Development of a non invasive NGF-based therapy for Alzheimer's disease [J]. Curr Alzheimer Res, 2009, 6(2): 158-170.
35 高之旭,盛建华. 痴呆病人的行为和精神症状及治疗进展[J]. 中国神经精神疾病杂志, 2000, 26(6): 382-383.
36 WangH Y, CrupiD, LiuJ, et al. Repetitive transcranial magnetic stimulation enhances BDNF-TrkB signaling in both brain and lymphocyte [J]. J Neurosci, 2011, 31(30): 11044-11054.
37 TanT, XieJ, LiuT, et al. Low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) reverses Abeta(1-42)-mediated memory deficits in rats [J]. Exp Gerontol, 2013, 48(8): 786-794.
38 YueL, Xiao-linH, TaoS. The effects of chronic repetitive transcranial magnetic stimulation on glutamate and gamma-aminobutyric acid in rat brain [J]. Brain Res, 2009, 1260: 94-99.
39 StrafellaA P, PausT, FraraccioM, et al. Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex [J]. Brain, 2003,126(Pt 12): 2609-2615.
40 KannoM, MatsumotoM, TogashiH, et al. Effects of acute repetitive transcranial magnetic stimulation on extracellular serotonin concentration in the rat prefrontal cortex [J]. J Pharmacol Sci, 2003, 93(4): 451-457.
41 KoffieR M, Meyer-LuehmannM, HashimotoT, et al. Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques [J]. Proc Natl Acad Sci U S A, 2009, 106(10): 4012-4017.
42 HuangZ, TanT, DuY, et al. Low-frequency repetitive transcranial magnetic stimulation ameliorates cognitive function and synaptic plasticity in APP23/PS45 mouse model of Alzheimer's disease [J]. Front Aging Neurosci, 2017, 9: 292.
43 KimD, YoonY C, ChaeS A, et al. High-frequency magnetic stimulation attenuates beta-amyloid protein 1-42 neurotoxicity in organotypic hippocampal slices [J]. Neural Regen Res, 2010, 5(18): 1365-1372.
44 SagareA P, BellR D, ZlokovicB V. Neurovascular defects and faulty amyloid-beta vascular clearance in Alzheimer's disease [J]. J Alzheimers Dis, 2013, 33(1): S87-S100.
45 GuseB, FalkaiP, WobrockT. Cognitive effects of high-frequency repetitive transcranial magnetic stimulation: a systematic review [J]. J Neural Transm (Vienna), 2010, 117(1): 105-122.
46 DevanandD P, Van HeertumR L, KegelesL S, et al. (99m)Tc hexamethyl-propylene-aminoxime single-photon emission computed tomography prediction of conversion from mild cognitive impairment to Alzheimer disease [J]. Am J Geriatr Psychiatry, 2010, 18(11): 959-972.
47 柴宁,王岚,王学义. 重复经颅磁刺激治疗阿尔茨海默病的研究进展[J]. 中华精神科杂志, 2013, 46(2): 126-128.
Outlines

/

〈 〉