《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (8): 936-939.doi: 10.3969/j.issn.1006-9771.2019.08.010

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Evaluation for Parkinson's Disease with Chinese Version of MDS-UPDRS and Original UPDRS

QU Yan, LI Xiao-hong, SUN Ya-nan, LI Ya-hui   

  1. Dalian Friendship Hospital, Dalian, Liaoning 116001, China
  • Received:2019-05-22 Revised:2019-06-16 Published:2019-08-25 Online:2019-08-16
  • Contact: LI Xiao-hong, E-mail: xhlihh@126.com
  • Supported by:
    Supported by Dalian Medical Science Research Project (No. 1611029)

Abstract: Objective To evaluate the reliability and validity of Chinese version of International Parkinson and Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (UPDRS), and then do comparative analysis with original UPDRS. Methods From May, 2016 to December, 2018, 225 patients with Parkinson's disease were respectively evaluated by MDS-UPDRS and UPDRS, and then the reliability and validity of MDS-UPDRS were evaluated. Correlation between two scales was analyzed. Results The Cronbach's coefficient of the total MDS-UPDRS was 0.734. Rank correlation's coefficient was 0.905. For factor analysis, KMO was 0.728. Pearson's correlation analysis showed that the correlation's coefficient of the common factor of the two scales was 0.969, while the correlation's coefficient of the total score of the two scales was 0.972. Compared with UPDRS, MDS-UPDRS added a number of non-motor symptoms, which adjusted the standard of measurement and increased the accuracy degree of evaluation at early stage of disease. Besides, MDS-UPDRS added a lot of instructions to evaluate the standards to make the evaluation normatively. Conclusion Chinese version of MDS-UPDRS has high reliability and validity, and highly correlate with the original UPDRS. It is more suitable for Chinese patients with Parkinson's disease in clinical evaluation than UPDRS.

Key words: Parkinson's disease, Chinese version of International Parkinson and Movement Disorder Society-Unified Parkinson's Disease Rating Scale, Unified Parkinson's Disease Rating Scale

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