《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2021, Vol. 27 ›› Issue (6): 706-711.doi: 10.3969/j.issn.1006-9771.2021.06.012

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Survey of Neurological Function and Complications of Pediatric Spinal Cord Injury

Ying ZHANG1,2(),Hong-jun ZHOU1,2,Gen-lin LIU1,2,Ying ZHENG1,2,Xiao-lei LU1,2,Hai-qiong KANG1,2,Chun-xia HAO1,2,Bo WEI1,2,Yi-ji WANG1,2,Yuan YUAN1,2,Qian-ru MENG1,2,Jian-jun LI3,4,5   

  1. 1.Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
    2.Beijing Bo'ai Hospital, China Research Centre, Beijing 100068, China
    3.China Rehabilitation Science Institute, Beijing 100068, China
    4.Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China
    5.Center of Neural Injury and Repair, Beijing 100068, China
  • Received:2020-10-19 Revised:2020-12-28 Published:2021-06-25 Online:2021-06-21
  • Contact: Ying ZHANG E-mail:iamzhangying@tom.com
  • Supported by:
    Fundamental Research Funds for Central Public Welfare Research Institutes(2015CZ-25)

Abstract: Objective

To investigate the outcome of neurological function and the clinical characteristics of complications in children with spinal cord injury.

Methods

From 2011 to 2019, children under 15 years old with spinal cord injury were selected in our hospital. Their level of injury and American Spinal Injury Association Impairment Scale (AIS) at one month, three months and one year were recorded. And the complications such as pressure ulcers/scald, urinary tract infection, hydronephrosis/vesicoureteral reflux, constipation, osteoporosis/fracture, deep vein thrombosis, neurodynia, heterotopic ossification, scoliosis and hip dysplasia were analyzed.

Results

Of 159 individuals, 41 were boys and 118 were girls, the average age at injury was (6.08±2.57) years. The main cause of spinal cord injury was sports accidents (47.8%), and the main injury sites were thoracic spinal cord injury (89.3%). The cause of spinal cord injury was correlated with age at injury (r = -0.160, P = 0.044), gender (r = -0.458, P < 0.001) and injury sites (r = -0.249, P = 0.002). Complete spinal cord injury counted for 71.7%, and the AIS grade at one month was correlated with that at twelve months (r = 0.984, P < 0.001). The main complications were urinary tract infection (69.2%), constipation (67.9%), hydronephrosis/vesicoureteral reflux (37.7%), scoliosis (25.8%) and hip dysplasia (25.2%). The incidence of ulcers/scald was correlated with injury site (r = 0.179, P = 0.024). The AIS grade three months after injury was significantly correlated with urinary tract infection, constipation, scoliosis and hip dysplasia (|r| > 0.227, P < 0.01). The incidence of ulcers/scald was correlated with osteoporosis/fracture (r = 0.208, P < 0.01). The incidence of urinary tract infection was significantly correlated with hydronephrosis/vesicoureteral reflux, constipation, scoliosis and hip dysplasia (r > 0.261, P < 0.001), as well as osteoporosis/fracture (r = 0.195, P < 0.05). The incidence of hydronephrosis/vesicoureteral reflux was significantly correlated with constipation, osteoporosis/fracture, scoliosis and hip dysplasia (r > 0.146, P < 0.01). The incidence of constipation was significantly correlated with scoliosis and hip dysplasia (r > 0.313, P < 0.01), as well as osteoporosis/fracture (r = 0.160, P < 0.05). The incidence of osteoporosis/fracture was significantly correlated with scoliosis and hip dysplasia (r > 0.342, P < 0.01). The incidence of scoliosis was significantly correlated with hip dysplasia (r = 0.818, P < 0.001).

Conclusion

The recovery of neurological function after spinal cord injury in children is closely correlated to AIS. The outcome of complete spinal cord injury is poor. The common complications after spinal cord injury in children demonstrate specific age characteristics, and the incidence of urinary tract infection, constipation, hydronephrosis/vesicoureteral reflux, scoliosis and hip dysplasia are common complications, which need more attention.

Key words: spinal cord injury, children, function, complication, prognosis

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