有氧运动对注意缺陷多动障碍儿童核心症状和执行功能的影响

doi:10.3969/j.issn.1006-9771.2022.06.012

Abstract

Abstract:

Objective To observe the effect of aerobic exercise on core symptoms and executive function in children with attention deficit hyperactivity disorder (ADHD). Methods From June, 2020 to December, 2021, 64 children with ADHD at outpatient in Dushu Lake Hospital were randomly divided into control group (n = 32) and observation group (n = 32). The control group sat down and watched the cartoon for 20 minutes, and the observation group performed cycling exercise while watching the cartoon, for twelve weeks. The core symptoms were assessed with Conners Parent Symptom Questionnaire (PSQ), while the inhibition, conversion and refresh functions were assessed with the psychological test software E-Prime 2.0 system. Results After twelve weeks of treatment, the PSQ factor scores decreased in the observation group (t > 4.775, P < 0.001), and were lower than that of the the control group (t > 3.184, P < 0.001). The response time and accuracy of inhibition, conversion, and refresh functions decreased in the observation group (t > 2.259, P < 0.05), and were lower than that of the control group (t > 2.007, P < 0.05). Conclusion Aerobic exercise could reduce the core symptoms of poor attention and hyperactivity impulsivity, and improve the executive functioning in children with ADHD.

Key words: attention deficit and hyperactivity disorde, aerobic exercise, executive function, core symptom

CLC Number:

R749.94

CHEN Xiaoming,LIANG Guanjun,LI Mingdi,WANG Qingjuan,SU Min. Effect of aerobic exercise on core symptoms and executive function in children with attention deficit hyperactivity disorder[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(6): 704-709.

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References 32

[1]	支金草, 张世雯, 黄美灵, 等. 导致儿童注意力缺陷多动障碍的孕期和围产期危险因素Scoping综述[J]. 中国康复理论与实践, 2022, 28(1): 79-89.
	ZHI J C, ZHANG S W, HUANG M L, et al. Risk factors during pregnancy and perinatal period for attention deficit hyperactivity disorder in children: a scoping review[J]. Chin J Rehabil Theory Pract, 2022, 28(1): 79-89.
[2]	丁利, 车月苹, 周斯斯, 等. 注意缺陷多动障碍儿童社会功能和父母焦虑情绪的关系及团体父母行为训练的效果[J]. 中国康复医学杂志, 2021, 36(2): 214-216.
	DING L, CHE Y P, ZHOU S S, et al. Chin J Rehabil Med, 2021, 36(2): 214-216.
[3]	CHEN K, PHIPPS S. "Why can't you sit still?"The effect of daily physical activity on childhood inattention/hyperactivity and the educational gender gap[J]. Soc Sci Med, 2021, 284: 114232. doi: 10.1016/j.socscimed.2021.114232
[4]	李世明, 冯为, 方芳, 等. 中国儿童注意缺陷多动障碍患病率Meta分析[J]. 中华流行病学杂志, 2018, 39(7): 993-998.
	LI S M, FENG W, FANG F, et al. Prevalence of attention deficit and hyperactivity disorder in children in China: a systematic review and meta-analysis[J]. Chin J Epidemiol, 2018, 39(7): 993-998.
[5]	RAMAN S R, MAN K K C, BAHMANYAR S, et al. Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases[J]. Lancet Psychiatry, 2018, 5(10): 824-835. doi: 10.1016/S2215-0366(18)30293-1
[6]	EKHART C, VRIES T, HUNSEL F V. Psychiatric adverse drug reactions in the paediatric population[J]. Arch Dis Child, 2020, 105(8): 749-755. doi: 10.1136/archdischild-2019-317933
[7]	CHRISTIANSEN L, BECK M M, BILENBERG N, et al. Effects of exercise on cognitive performance in children and adolescents with ADHD: potential mechanisms and evidence-based recommendations[J]. J Clin Med, 2019, 8(6): 841. doi: 10.3390/jcm8060841
[8]	NEUDECKER C, MEWES N, REIMERS A K, et al. Exercise interventions in children and adolescents with ADHD: a systematic review[J]. J Atten Disord, 2019, 23(4): 307-324. doi: 10.1177/1087054715584053
[9]	许明超, 蒋长好. 身体活动改善注意缺陷多动障碍儿童认知神经功能的系统综述[J]. 中国康复理论与实践, 2021, 27(12): 1422-1429.
	XU M C, JIANG C H. Effects of physical activity on cognitive and neurological function of attention deficit hyperactivity disorder children: a systematic review[J]. Chin J Rehabil Theory Pract, 2021, 27(12): 1422-1429.
[10]	DOERNBERG E, HOLLANDER E. Neurodevelopmental disorders (ASD and ADHD): DSM-5, ICD-10, and ICD-11[J]. CNS Spectr, 2016, 21(4): 295-299. doi: 10.1017/S1092852916000262
[11]	MIKLÓS M, KOMÁROMY D, FUTÓ J, et al. Acute physical activity, executive function, and attention performance in children with attention-deficit hyperactivity disorder and typically developing children: an experimental study[J]. Int J Environ Res Public Health, 2020, 17(11): 4071. doi: 10.3390/ijerph17114071
[12]	范娟, 杜亚松, 王立伟. Conners父母用症状问卷的中国城市常模和信度研究[J]. 上海精神医学, 2005, 17(6): 321-323.
	FAN J, DU Y S, WANG L W. The norm and reliability of the Conners Parent Symptom Questionnaire in Chinese urban children[J]. Shanghai Arch Psych, 2005, 17(6): 321-323.
[13]	BENZING V, SCHMIDT M. The effect of exergaming on executive functions in children with ADHD: a randomized clinical trial[J]. Scand J Med Sci Sports, 2019, 29(8): 1243-1253. doi: 10.1111/sms.13446
[14]	WANG H, HE W, WU J, et al. A coordinate-based meta-analysis of the n-back working memory paradigm using activation likelihood estimation[J]. Brain Cogn, 2019, 132: 1-12. doi: 10.1016/j.bandc.2019.01.002
[15]	TIAN S, MOU H, FANG Q, et al. Comparison of the sustainability effects of high-intensity interval exercise and moderate-intensity continuous exercise on cognitive flexibility[J]. Int J Environ Res Public Health, 2021, 18(18): 9631. doi: 10.3390/ijerph18189631
[16]	XING B, LI Y C, GAO W J. Norepinephrine versus dopamine and their interaction in modulating synaptic function in the prefrontal cortex[J]. Brain Res, 2016, 1641(Pt B): 217-233.
[17]	SILVERSTEIN M J, FARAONE S V, LEON T L, et al. The relationship between executive function deficits and DSM-5-defined ADHD symptoms[J]. J Atten Disord, 2020, 24(1): 41-51. doi: 10.1177/1087054718804347
[18]	VON RHEIN D, BECKMANN C F, FRANKE B, et al. Network-level assessment of reward-related activation in patients with ADHD and healthy individuals[J]. Hum Brain Mapp, 2017, 38(5): 2359-2369. doi: 10.1002/hbm.23522
[19]	BELLATO A, ARORA I, HOLLIS C, et al. Is autonomic nervous system function atypical in attention deficit hyperactivity disorder (ADHD)? A systematic review of the evidence[J]. Neurosci Biobehav Rev, 2020, 108: 182-206. doi: 10.1016/j.neubiorev.2019.11.001
[20]	RUBIA K. Cognitive neuroscience of attention deficit hyperactivity disorder (ADHD) and its clinical translation[J]. Front Hum Neurosci, 2018, 12: 100. doi: 10.3389/fncom.2018.00100
[21]	熊健, 郑国华. 脑卒中患者执行功能的研究进展[J]. 中国康复理论与实践, 2020, 26(7): 797-801.
	XIONG J, ZHENG G H. Advance in executive function for post-stroke patients (review)[J]. Chin J Rehabil Theory Pract, 2020, 26(7): 797-801.
[22]	DIAMOND A. Executive functions[J]. Ann Rev Psychol, 2013, 64: 135-168. doi: 10.1146/annurev-psych-113011-143750
[23]	王茹, 刘楠, 李卫萍, 等. 有氧运动对脑小血管病大鼠执行功能的效果[J]. 中国康复理论与实践, 2019, 25(3): 249-254.
	WANG R, LIU N, LI W P, et al. Effect of aerobic exercise on behavioral function in rats with cerebral small vessel disease[J]. Chin J Rehabil Theory Pract, 2019, 25(3): 249-254.
[24]	LUDYGA S, BRAND S, GERBER M, et al. An event-related potential investigation of the acute effects of aerobic and coordinative exercise on inhibitory control in children with ADHD[J]. Dev Cogn Neurosci, 2017, 28: 21-28. doi: 10.1016/j.dcn.2017.10.007
[25]	KHODAVERDI Z, MOREAU D, GARBER C E. Is there an effective dose of aerobic exercise associated with better executive function in youth with attention deficit hyperactivity disorder?[J]. Child Neuropsychol, 2022, 28(5): 569-596. doi: 10.1080/09297049.2021.1992378
[26]	CHANG Y K, ERICKSON K I, STAMATAKIS E, et al. How the 2018 US Physical Activity Guidelines are a call to promote and better understand acute physical activity for cognitive function gains[J]. Sports Med, 2019, 49(11): 1625-1627. doi: 10.1007/s40279-019-01190-x
[27]	PONTIFEX M B, SALIBA B J, RAINE L B, et al. Exercise improves behavioral, neurocognstive, and scholastic performance in children with attention-deficit/hyperactivity disorder[J]. J Pediatr, 2013, 162(3): 543-551. doi: 10.1016/j.jpeds.2012.08.036
[28]	LUDYGA S, GERBER M, MÜCKE M, et al. The acute effects of aerobic exercise on cognitive flexibility and task-related heart rate variability in children with ADHD and healthy controls[J]. J Atten Disord, 2020, 24(5): 693-703. doi: 10.1177/1087054718757647
[29]	SEIFFER B, HAUTZINGER M, ULRICH R, et al. The efficacy of physical activity for children with attention deficit hyperactivity disorder: a meta-analysis of randomized controlled trials[J]. J Atten Disord, 2022, 26(5): 656-673. doi: 10.1177/10870547211017982
[30]	CHRISTIANSEN L, BECK M M, BILENBERG N, et al. Effects of exercise on cognitive performance in children and adolescents with ADHD: potential mechanisms and evidence-based recommendations[J]. J Clin Med, 2019, 8(6): 841. doi: 10.3390/jcm8060841
[31]	尹苗苗, 张玥, 杨风英, 等. 有氧运动训练对中度脑外伤患者认知功能的影响[J]. 中华物理医学与康复杂志, 2016, 38(9): 707-708.
	YIN M M, ZHANG Y, YANG F Y, et al. Chin J Phys Med Rehabil, 2016, 38(9): 707-708.
[32]	邹华, 匡桂芳, 辛晓昱, 等. 注意缺陷多动障碍儿童的智力特点[J]. 中国康复理论与实践, 2013, 19(7): 694-695.
	ZOU H, KUANG G F, XIN X Y, et al. Intellectual characteristics of children with attention deficit hyperactivity disorder[J]. Chin J Rehabil Theory Pract, 2013, 19(7): 694-695.

组别	n	性别(男/女)/n	年龄/岁	病程/月	分型(注意缺陷/多动冲动/混合)/n	IQ
对照组	32	27/5	7.89±2.13	10.5±7.3	5/10/17	89±17
观察组	32	26/6	8.37±1.68	11.6±9.7	6/8/18	97±12
χ²/t值		0.110	1.001	0.512	1.589	1.631
P值		0.740	0.321	0.610	0.207	0.108

组别	n	品行问题		多动冲动		多动指数		t值^a	P值^a	t值^b	P值^b	t值^c	P值^c
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	t值^a	P值^a	t值^b	P值^b	t值^c	P值^c
对照组	32	1.37±0.39	1.31±0.43	2.21±0.64	2.08±0.28	2.16±0.54	2.19±0.43	0.585	0.561	1.053	0.297	0.246	0.807
观察组	32	1.40±0.36	1.03±0.25	2.23±0.57	1.22±0.35	2.13±0.35	1.15±0.32	4.775	< 0.001	8.542	< 0.001	11.690	< 0.001
t值		0.320	3.184	0.132	10.854	0.264	12.294
P值		0.750	0.002	0.895	< 0.001	0.793	< 0.001

组别	n	反应时/ms		精确度/%		t值^a	P值^a	t值^b	P值^b
组别	n	治疗前	治疗后	治疗前	治疗后	t值^a	P值^a	t值^b	P值^b
对照组	32	118.58±7.56	115.58±8.89	3.15±2.93	3.23±2.82	1.454	0.151	0.111	0.912
观察组	32	115.31±12.45	97.63±9.46	3.67±2.73	2.13±2.29	6.396	< 0.001	2.885	0.005
t值		1.270	7.822	0.735	2.007
P值		0.209	< 0.001	0.465	0.049

组别	n	反应时/ms		精确度/%		t值^a	P值^a	t值^b	P值^b
组别	n	治疗前	治疗后	治疗前	治疗后	t值^a	P值^a	t值^b	P值^b
对照组	32	206.07±73.40	191.81±44.25	9.03±4.06	8.85±3.27	0.941	0.350	0.195	0.846
观察组	32	224.56±97.54	158.33±58.63	8.72±3.61	7.05±2.11	3.292	0.002	2.259	0.027
t值		0.857	2.578	0.323	2.616
P值		0.395	0.012	0.748	0.011

组别	n	反应时/ms		精确度/%		t值^a	P值^a	t值^b	P值^b
组别	n	治疗前	治疗后	治疗前	治疗后	t值^a	P值^a	t值^b	P值^b
对照组	32	174.61±35.83	176.35±35.83	4.37±2.19	4.15±2.46	0.194	0.847	0.378	0.707
观察组	32	178.79±33.13	151.26±32.60	4.23±2.36	2.29±2.34	3.351	0.001	3.302	0.002
t值		0.485	2.930	0.246	3.099
P值		0.630	0.005	0.807	0.003

Effect of aerobic exercise on core symptoms and executive function in children with attention deficit hyperactivity disorder

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