座椅前倾对脑卒中患者坐-站转移能力的影响及脑网络研究

doi:10.3969/j.issn.1006-9771.2026.09.008

Abstract

Abstract:

Objective To observe the clinical effect of anterior seat inclination on sit-to-stand (STS) ability and balance function in patients with stroke, as well as brain functional connectivity based on functional near-infrared spectroscopy (fNIRS).

Methods From January, 2024 to December, 2025, 43 patients with stroke were randomly divided into control group (n = 21) and experimental group (n= 22). The control group received conventional rehabilitation combined with STS training on a flat seat, while the experimental group received conventional rehabilitation plus STS training with a 20° anterior seat inclination, for two weeks. Five-times sit-to-stand test (FTSST) and Berg Balance Scale (BBS) were assessed before and after training. fNIRS was used to detect changes in cerebral blood oxygenation in the prefrontal cortex (PFC), primary motor cortex (M1), primary somatosensory cortex (S1) and premotor cortex (PMC), and to analyze functional connectivity strength.

Results After training, FTSST time shortened in both groups (t > 3.469, P < 0.01), and was shorter in the experimental group than in the control group (t = -2.065, P < 0.05); BBS scores increased in both groups (|Z| > 4.019, P< 0.01), and was higher in the experimental group than in the control group (Z = -2.250, P < 0.05). fNIRS showed that after training, the functional connectivity strength between the left M1 and the right PFC increased, as well as between the left M1 and the right S1 in the experimental group (t > 3.311, P< 0.05).

Conclusion STS training with anterior seat inclination can enhance functional connectivity in relevant brain regions, which may contribute to improvements of STS ability and balance function in patients with stroke.

Key words: stroke, sit-to-stand transition, seat inclination, functional near-infrared spectroscopy, brain functional networks

CLC Number:

R743.3

Shen Xiaohua, Chen Fangyuan, Rong Jifeng, Rao Biaoqin, Kong Lingxuan, Tian Wei, Chen Zhiqun, Li Li. Effect of anterior seat inclination on sit-to-stand ability in patients with stroke and related brain network[J]. Chinese Journal of Rehabilitation Theory and Practice, 2026, 32(9): 1061-1067.

Figures/Tables 5

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Figure 1

References 28

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组别	n	性别(男/女)/n	年龄/岁	卒中类型(梗死/出血)/n	大脑半球受损(左/右)/n	病程/d
对照组	21	11/10	69.00(65.50, 72.50)	16/5	9/12	101.00(35.00, 158.50)
试验组	22	16/6	67.50(61.00, 71.00)	15/7	10/12	111.50(60.00, 187.25)
χ²/Z值		1.904	-0.887	0.343	0.029	0.620
P值		0.168	0.380	0.558	0.864	0.535

组别	n	测试	$\stackrel{-}{\mathit{x}}\pm \mathit{s}$	t值	P值
对照组	21	前测	24.819±8.209	3.469	0.002
		后测	22.236±6.462
试验组	22	前测	23.658±6.020	7.441	< 0.001
		后测	18.615±4.971
训练前两组均值差			-1.161±2.188	-0.531	0.599
训练后两组均值差			-3.620±1.753	-2.065	0.045

组别	n	测试	M(Q_L, Q_U)	Z值	P值
对照组	21	前测	27.00(22.00, 32.00)	-4.019	< 0.001
		后测	34.00(30.00, 41.50)
试验组	22	前测	32.50(22.50, 38.50)	-4.111	< 0.001
		后测	43.50(32.00, 48.25)
训练前两组差值				-1.460	0.144
训练后两组差值				-2.250	0.024

ROI-ROI	训练前	训练后	t值	P值
左PMC-右PMC	0.651±0.437	0.677±0.472	-0.321	0.962
左PMC-左S1	0.809±0.339	0.847±0.401	-0.639	0.921
左PMC-左PFC	0.579±0.370	0.531±0.334	0.797	0.921
左PMC-右PFC	0.531±0.329	0.465±0.283	1.434	0.563
左PMC-左M1	0.926±0.402	0.913±0.381	0.204	0.962
左PMC-右M1	0.708±0.464	0.711±0.435	-0.042	0.982
左PMC-右S1	0.646±0.377	0.581±0.418	1.384	0.563
右PMC-左S1	0.614±0.426	0.657±0.472	-0.544	0.921
右PMC-左PFC	0.532±0.354	0.540±0.319	-0.113	0.981
右PMC-右PFC	0.595±0.398	0.573±0.342	0.280	0.962
右PMC-左M1	0.718±0.557	0.639±0.484	0.808	0.921
右PMC-右M1	0.962±0.469	0.831±0.529	1.399	0.563
右PMC-右S1	0.794±0.456	0.740±0.464	0.671	0.921
左S1-左PFC	0.599±0.337	0.573±0.348	0.453	0.962
左S1-右PFC	0.554±0.309	0.522±0.330	0.591	0.921
左S1-左M1	0.915±0.383	0.840±0.381	1.156	0.663
左S1-右M1	0.732±0.454	0.812±0.390	-1.254	0.626
左S1-右S1	0.691±0.408	0.780±0.430	-1.578	0.563
左PFC-右PFC	0.641±0.357	0.651±0.286	-0.180	0.962
左PFC-左M1	0.581±0.342	0.454±0.317	2.942	0.073
左PFC-右M1	0.552±0.356	0.553±0.318	-0.023	0.981
左PFC-右S1	0.555±0.336	0.637±0.305	-1.814	0.563
右PFC-左M1	0.574±0.322	0.407±0.315	4.224	0.011
右PFC-右M1	0.586±0.340	0.552±0.333	0.548	0.921
右PFC-右S1	0.643±0.340	0.630±0.357	0.249	0.962
左M1-右M1	0.892±0.527	0.771±0.479	1.680	0.563
左M1-右S1	0.755±0.450	0.555±0.437	3.311	0.047
右M1-右S1	0.849±0.491	0.874±0.477	-0.388	0.962

Effect of anterior seat inclination on sit-to-stand ability in patients with stroke and related brain network

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