《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2002, Vol. 8 ›› Issue (03): 132-133.

• 础基研究 • Previous Articles     Next Articles

The clinical study of immune state in cervical spinal cord injury

ZHANG Jian-hong,FAN Jian-zhou,DENG Ai-wen,et al   

  1. The Department of Rehabilitation Medicine,Nanfang Hospital of the First Military Medicine University,Guangzhou 510515,Guangdong China
  • Received:2001-08-15 Published:2002-03-25 Online:2002-03-25

Abstract: ObjectiveTo measure the level of T lymphocyte subsets and immunoglobulin in cervical spinal cord injury. Methods36 cases with cervical spinal cord injury were measured in T lymphocyte subsets and immunoglobulin of vein blood before and after the rehabilitation therapy. By comparing with control group, the state of immune functional in the injury was analyzed.ResultsThe cellular and humoral immune were inhibited distinctly. The level of CD3+,CD4+,CD4+/CD8+ and IgG of TBI group were lower than the level of control group. The CD3+ and CD4+/CD8+ were improved after treatment. The immune state of complete injury was inhibited more seriously than incomplete injury. ConclusionsThe cellular and humoral immune of cervical spinal cord injury were inhibited. The more seriously of the injury, the more inhibited of immune function.

Key words: spinal cord injury, T lymphocyte subsets, immunoglobulin, assessment