《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2003, Vol. 9 ›› Issue (06): 328-329.

• 神经康复 • Previous Articles     Next Articles

Observation of botulinum toxin A applying in treatment of spastic cerebral palsy

DU Feng-zhen,LU Sheng-lu,WANG Hui-ying,et al   

  1. Institute of Cerebral Palsy Rehabilitation of Gansu Rehabilitation Center,Lanzhou 730000,Gansu,China
  • Received:2003-03-18 Published:2003-06-25 Online:2003-06-25

Abstract: ObjectiveTo observe the effect of botulinum toxin A (BTX-A) in rehabilitation training on cerebral palsy (CP).Methods47 CP children were randomly divided into the treatment group (32 cases) and control group (15 cases). Both groups were received rehabilitation training. But cases of the treatment group were injected with BTX-A in part of spastic muscles. Angles of inner contraction muscle (AICM) and activities of daily living (ADL) of two groups were observed for 6 months.ResultsImprovements of AICM and ADL in the treatment group were significantly better than that in the control group (P<0.01).Conclusions The rehabilitation training still is a kind of efficient treatment method. BTX-A injecting in part of spastic muscles is a kind of efficient assistant method and furnishes a better chance for rehabilitation training. Rehabilitation training combining with BTX-A injection can clearly curtail period of treatment, raise curative effect. BTX-A injection has significant applicable value in treatment on cerebral palsy.

Key words: cerebral palsy, botulinum toxin A(BTX-A), spasm, activities of daily living (ADL)