CJRTP

《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2003, Vol. 9 ›› Issue (10): 598-599.

• 基础研究 • Previous Articles     Next Articles

Studies on the protective effect of drug serum taken from rats administered with Naofucong in PC12 cell ischemic model

ZHANG Meng-ren, XUHui-yuan, GUO Sai-shan, et al   

  1. Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2003-08-11 Published:2003-10-25 Online:2003-10-25

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Abstract: ObjectiveTo examine effects of traditional Chinese herbs Naofucong grain on PC12 cells injured by H2O2 in vitro MethodsRats random divided into 2 groups: Naofucong grain treating group (administered with Naofucong grain) and control group (administered with distilled water) After 3 days administration, serums were obtained and added to cultured PC12 cells which were under different concentrations of H2O2 Morphological examinations in PC12 cells were detected by MTT measurement ResultsMTT measurement showed that Naofucong grain administered rats serums significantly increased the survival number of PC12 cells in different concentrations of H2O2.Conclusion Naofucong grain may have obvious protective effects on PC12 cells injured by H2O2.

Key words: traditional Chinese herbs, Naofucong, drug serum, PC12 cells, ischemic model