Abstract: ObjectiveTo observe effect of etomidate and ketamine on the cardiovascular function of children with cerebral palsy.Methods84 cerebral palsy cases were divided randomly into the etomidate group and ketamine group with 42 cases in each group, when they were treated with lower extremity orthopedic operation and anaesthetized by extradural continuous block anesthesia. The etomidate group was injected with etomidate and ketamine group was injected with ketamine. The heart rate variability (HRV) was recorded during anesthesia course.ResultsHeart rate and HRV of the etomidate group decreased significantly (P<0.05-0.01), but that of the ketamine group had no significantly differences (P>0.05).ConclusionEtomidate has a significant influence on cerebral palsy children's cardiovascular function in anesthesia course.

Key words: cerebral palsy, heart rate variability, anesthesia