《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2005, Vol. 11 ›› Issue (05): 402-403.

• 临床观察 • Previous Articles     Next Articles

Severe cognitive deficit caused by Topiramate

SUN Wei,WANG Wei-wei,WU Xun   

  1. Department of Neurology,Peking University First Hospital,Beijing 100034,China
  • Received:2005-01-13 Published:2005-05-25 Online:2005-05-25

Abstract: ObjectiveTo investigate the character of severe cognitive deficit caused by topiramate(TPM) administration in epileptic patients.Methods3 epileptic patients who suffered from severe cognitive deficit following topramate treatment were analyzed.Results and ConclusionTheir verbal functions were often affected especially the fluency of speech, as well as their memory and calculation.

Key words: Topiramate, epilepsy, cognitive deficit, side effect