Abstract: ObjectiveTo observe effects of Naotong(NT) oral solution on the somatosensory evoked potentials(SEP) of acute cerebral infarction rats and its curative experimental.Methods24 model rats were randomly divided into three groups and treated with NT oral solution,Naoxuekang(NXK) and normal saline(NS) respectively for 20 days,the SEP and neurologic grades of the rat models were evaluated before and after treatment.ResultsAll the latencies of SEP(P₁,N₂,P₂) in NT group was shorter than that of the pre-treatment and NS control group(P<0.01).The neurologic grades of both NT and NXK groups were highly lowered compared with pre-treatment and NS control group(both P<0.05).The latencies of SEP in the model rats were highly correlated with the neurologic grades(r=0.97～0.99,P<0.05～0.01).ConclusionNT can accelerate the nervous function recovery of the rat models with acute cerebral infarction.SEP may be used as a powerful index of observation on curative effect of acute cerebral infarction.

Key words: Naotong oral solution, cerebral infarction, somatosensory evoked potentials(SEP), rat