《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2006, Vol. 12 ›› Issue (08): 694-695.
• 基础研究 • Previous Articles Next Articles
ZHANG Lin-xi, YI Cheng-gang,ZHANG Xu-dong, et al
Received:
Published:
Online:
Abstract: ObjectiveTo identify differential genes of malignant melanoma using gene chip expression profiles.MethodsAgilent Human 1A OligoDNA was employed to find out difference in gene expression between malignant melanoma and nevus. The total RNA was isolated from two type tissues, labled the fluorescent to the probe, hybridized, washed and analyzed.ResultsAmong the 21073 target genes, 1596 genes were differentially expressed in malignant melanoma, including 733 genes up-regulated, and 863 down-regulated.ConclusionThe gene chip technique can screen genes that may be specifically expressed in malignant melanoma.
Key words: gene chip technique, malignant melanoma, nevus, differential gene
ZHANG Lin-xi;YI Cheng-gang;ZHANG Xu-dong;et al. Study of Screening Differential Genes of Malignant Melanoma Using Gene Chip Expression Profiles [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2006, 12(08): 694-695.
0 / / Recommend
Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks
URL: https://www.cjrtponline.com/EN/
https://www.cjrtponline.com/EN/Y2006/V12/I08/694