Abstract: The study of brain's functional localization is one of the fastest developing domain of the neuroscience. It brings a new prospect of cognition, thinking and diagnosis and treatment of various nervous disease. Now, it is used widespreadly in neurosurgery, cognation, rehabilitation and social psychology, and etc. The article is a review concerning on the progression of clinical application and related studies of brain's functional localization.

Key words: brain's functional localization, imaging examination, review