Abstract: Hepatocyte growth factor(HGF) is a mesenchyme-derived pleiotropic factor which regulates cell growth,cell motility,and morphogenesis of various types of cells,and is thus considered a humoral mediator of epithelial-mesenchymal interactions responsible for angiogenesis,apoptosis and oxidative stress,etc.This article reviewed the relationships between HGF and cardiovascular diseases.

Key words: hepatocyte growth factor, cadiocyte, endotheliocyte, ischemic heart disease, atherosclerotic disease, hypertension, heart transplantation, cardiac insufficiency, review