《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2006, Vol. 12 ›› Issue (12): 1054-1055.
• 基础研究 • Previous Articles Next Articles
YANG Jian,HONG Yi, DONG Hao, et al
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Abstract: Objective To investigate the possibility that bone marrow mesenchymal stem cells (BMSCs) differentiated into neuron-like cells induced by ganglioside in vitro.Methods BMSCs were separated, cultured and differentiate into neuron-like cells induced by ganglioside. Neuro-specific enolase (NSE) and neurofilament (NF) on the surface of differentiated and induced BMSCs were detected by immunocytochemistry.Results BMSCs were induced to differentiate into the cells with a typical neuronal morphology. The induced neuron-like cells expressed NSE and NF.Conclusion BMSCs can be differentiated into neuron-like cells by induction of ganglioside in vitro.
Key words: bone marrow mesenchymal stem cells (BMSCs), ganglioside, induced differentiation, neuron-like cells
YANG Jian;HONG Yi;DONG Hao;et al. Study of Bone Marrow Mesenchymal Stem Cells Differentiated into Neuron-like Cells Induced by Ganglioside in Vitro [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2006, 12(12): 1054-1055.
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