Abstract: Objective To observe the effect of “Shengbai Tablets” on increasing the numbers of leucocyte, enhancing lymphocyte proliferation and reducing the micronucleus rate of cells.Methods The leukopenia model of mouse was established with cyclophosphamide, and the changes of the leukocyte count, lymphocyte proliferation and micronucleus rate before and after Shengbai Tablets treatment were observed.Results After treatment, the leukocyte count, lymphocyte proliferation and micronucleus rate of the Shengbai Tablets group were ( 7.470 ±1.852)×10⁹/L, (14768.23±8316.86) and (6.02±1.72)‰ respectively, all were significantly better than that of the group without Shengbai Tablets treatment ( P<0.05～0.01).Conclusion Shengbai Tablets is able to increase the numbers of leucocyte, enhance the lymphocyte proliferation and reduce the micronucleus rate.

Key words: leukopenia, lymphocyte proliferation, micronucleus rate