Abstract: ObjectiveTo investigate the clinical characteristics of post-stroke depression (PSD) and correlative factors.Methods116 patients with PSD were randomly divided into the treatment group (n=69) and control group (n=47). The patients of the treatment group were treated with selective serotonin re-uptake inhibitors (SSRI) 20 mg/d and combined with psychological counselling, those of the control group only with SSRI. All patients were examined with Self-rating Depression Scale (SDS) when admission and one month after treatment.ResultsAfter treatment, the SDS scores of all patients in two groups decreased ( P<0.05～0.01), but the therapeutic effect of the treatment group was better than that of the control group ( P<0.05).ConclusionThe PSD is correlated with psych-social circumstances except body disease.

Key words: stroke, depressive symptom, correlation factor