《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2007, Vol. 13 ›› Issue (05): 430-431.
• 基础研究 • Previous Articles Next Articles
WANG Xing, LIN Yu-dong, WANG Ming-yuan, et al
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Abstract: Objective To investigate the proliferative activities and significance of Hodgkin's disease cells which were transfected with mtr Ⅱ gene. Methods The ki67 and proliferating cell nuclear antigen (PCNA) expression in Hodgkin's disease cells transfected with mtr Ⅱ gene were determined with immunohistochemistry. Results The ki67 and PCNA expression in cells transfected with mtr Ⅱ gene was more than that of cells without mtrⅡ gene transfected (P<0.05). Conclusion The proliferative activities of Hodgkin's disease cells transfected with mtr Ⅱ gene increased obviously, which may be related to the progress of Hodgkin's disease.
Key words: mtr Ⅱ gene, Hodgkin's disease, ki67 gene, proliferating cell nuclear antigen (PCNA)
WANG Xing;LIN Yu-dong;WANG Ming-yuan;et al. Proliferative Activities of Hodgkin's Disease Cells Transfected with mtrⅡ Gene [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2007, 13(05): 430-431.
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