Abstract: Objective To compare the effects of nerve block using diprospan, triamcinolone and lysinipirium on cervicogenic headache (CEH).Methods Sixty CEH patients were randomly divided into three groups (20 cases in each group), treated by occipital nerve block and C2 neural blockade with diprospan, triamcinolone and lysinipirium respectively, combined with a mixture of 0.4% lidocaine. All patients in three groups were evaluated by numeric rating scales (NRS) for pain degree and range of motion of the neck (ROM) before and after the nerve block.Results The scores of NRS decreased significantly and ROM improved in all groups after treatment ( P<0.01). There were no significant differences between diprospan group and triamcinolone group, but these two groups had a better effect than lysinipirium group ( P<0.01).Conclusion Nerve block using diprospan and triamcinolone can obtain a significant effect in the treatment of CEH.

Key words: cervicogenic headache, nerve block, treatment