《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2008, Vol. 14 ›› Issue (08): 710-712.

• 专题 • Previous Articles     Next Articles

Active Mechanism of Nogo and Intervention to Nogo Receptor (review)

LU Zhan-bin, SUN Lai-qing, CHEN Xian, et al   

  1. The Department of Spinal Cord Injury, the Second Hospial of Tangshan, Tangshan 063000, Hebei, China
  • Received:2008-03-10 Published:2008-08-01 Online:2008-08-01

Abstract: Nogo receptor is specific inhibiting factor conjuncted with myelin of central nervous system(CNS).After spinal cord injury,oligodendroglial cell and Nogo-A released from myelin inside cells inhibited the axonal regeneration.To analyze the intervention for Nogo receptor through molecule outside cell,information inside cell and gene,make clearing the inhibiting action of myelin-associated inhibiting factor-1,provide new thoughts and methods about axonal regeneration after spinal cord injury.

Key words: Nogo receptor, spinal cord injury, axonal, regeneration, review