《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2008, Vol. 14 ›› Issue (09): 872-873.
• 临床研究 • Previous Articles Next Articles
WANG Qiong,ZENG Zhao-xiang, ZHAI Jin-guo,et al
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Abstract: Objective To compare the efficacy and safety of mirtazapine and buspirone on panic disorder.Methods 86 cases with panic disorder were divided into two groups: the mirtazapine(30~60 mg/d) group and the buspirone(15~30 mg/d) group.Hamilton Anxiety Scale(HAMA) was adopted to evaluate the efficacy.Safety was evaluated with Treatment Emergent Symptom Scale(TESS),laboratorial and physical examination.Results The effective rate of mirtazapine group and buspirone group was 90.7% and 83.7% respectively 8 weeks after treatment(χ2=1.17,P>0.05).The scores of HAMA of the mirtazapine group decreased more than that of the buspirone group 1 or 2 weeks after treatment(tt=2.94,P<0.01 and t=2.49,P<0.05 respectively).At the end of wk,But there was not significant difference between two groups 4 or 8 weeks after treatment(P>0.05).Some mild side-effects were observed in both groups.Conclusion Mirtazapine shows a similar effect to buspirone and takes effect earlier on panic disorder.
Key words: panic disorder, mirtazapine, buspirone
WANG Qiong;ZENG Zhao-xiang;ZHAI Jin-guo;et al. Effects of Mirtazapine or Buspirone on Panic Disorder:A Parallel Control Study [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2008, 14(09): 872-873.
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