《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2008, Vol. 14 ›› Issue (10): 907-909.

• 专题 • Previous Articles     Next Articles

Advance in Research on Proteins Related with Brain Ischemia/Hypoxia Preconditioning and Their Functions(review)

LIULi-li, SU Ji-liang, NIU Jing-zhong   

  1. Taishan Chronic Disease Hospital, Tai'an 271000, Shandong, China
  • Received:2008-06-17 Published:2008-10-01 Online:2008-10-01

Abstract: Brain ischemia/hypoxia preconditioning(I/HPC) is one kind of endocardial protective phenomenon by organism against blood and oxygen deficit.Researches discovered various proteins such as hypoxic inducible factor-1(HIF-1),heat shock proteins(HSPs),erythropoietin(EPO),Bcl-2 family,calcitoningene related peptide(CGRP) and so on participated in brain I/HPC.This essay explains function and participating I/HPC mechanism of these proteins.

Key words: brain ischemia/hypoxia preconditioning, hypoxic inducible factor-1, heat shock protein, erythropoietin, function, review