Abstract: Mild cognitive impairment (MCI) represents a transitional status between the cognition of normal aging and the fully developed clinical features of dementia. It has a high risk to progress to Alzheimer disease. Neuroimaging has become increasingly important in the clinical assessment and early diagnosis of MCI. It can also predict the course of MCI and monitor treatment effects.

Key words: mild cognitive impairment, Alzheimer disease, neuroimaging, magnetic resonance imaging, structural imaging, functional imaging